A new Clonostachys Sp. ZBS49 filamentous fungus with high production of betulinic acid and its inhibitory effect on liver cancer cells

A new Clonostachys Sp. ZBS49 filamentous fungus with high production of betulinic acid and its inhibitory effect on liver cancer cells

Abstract Background Triterpenoid compounds such as betulinic acid (BA) and oleanolic acid (OA) exhibit considerable pharmacological activities. However, their current production primarily relies on plant extraction and chemical synthesis, methods that are often plagued by low efficiency, complex ext...

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Bibliographic Details
Main Authors: Luran Geng, Jiale Cui, Changyixin Xiao, Linlin Xu, Fengjiao Yue, Ting Zhang, Mengran Zhan, Zichang Lu, Yuzhe Ren, Chunsheng Wang, Jing Yin
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Microbial Cell Factories
Subjects:
Filamentous fungi
Betulinic acid
Fermentation system
Clonostachys Sp.
Genome
Tumor suppression
Online Access:https://doi.org/10.1186/s12934-025-02733-w
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