Collagen peptide markers for three extinct Australian megafauna species

Recent advancements in biomolecular archaeology, such as stable isotope and ancient DNA research, have expanded our understanding of megafauna extinction processes and dynamics. The rise of palaeoproteomics, specifically Zooarchaeology by Mass Spectrometry (ZooMS), has added yet another method to th...

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Main Authors: Carli Peters, Annette Oertle, Richard Gillespie, Nicole Boivin, Katerina Douka
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Mammal Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fmamm.2025.1564287/full
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author Carli Peters
Carli Peters
Annette Oertle
Annette Oertle
Richard Gillespie
Nicole Boivin
Nicole Boivin
Nicole Boivin
Katerina Douka
Katerina Douka
author_facet Carli Peters
Carli Peters
Annette Oertle
Annette Oertle
Richard Gillespie
Nicole Boivin
Nicole Boivin
Nicole Boivin
Katerina Douka
Katerina Douka
author_sort Carli Peters
collection DOAJ
description Recent advancements in biomolecular archaeology, such as stable isotope and ancient DNA research, have expanded our understanding of megafauna extinction processes and dynamics. The rise of palaeoproteomics, specifically Zooarchaeology by Mass Spectrometry (ZooMS), has added yet another method to this toolkit, as it can be used to taxonomically identify megafauna remains amongst highly fragmented bone assemblages. However, taxonomic identifications with ZooMS are reliant on the availability of collagen peptide markers for the regional fauna of interest. In the absence of a global reference database, most studies to date have been restricted to Eurasian contexts. Here, we report ZooMS peptide markers for three extinct Australian megafauna species: Zygomaturus trilobus, Palorchestes azael, and Protemnodon mamkurra. We show that these taxa can be differentiated from extant Australian fauna with these peptide markers. This foundational work represents an important step in establishing ZooMS as a method that can be used to identify new megafauna specimens in Australia’s highly fragmented fossil record and ultimately help resolve fundamental questions related to human–fauna–environment interactions.
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publisher Frontiers Media S.A.
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spelling doaj-art-967dbb2a4d05416c9ce50c4f7b825a982025-08-20T02:32:19ZengFrontiers Media S.A.Frontiers in Mammal Science2813-46992025-06-01410.3389/fmamm.2025.15642871564287Collagen peptide markers for three extinct Australian megafauna speciesCarli Peters0Carli Peters1Annette Oertle2Annette Oertle3Richard Gillespie4Nicole Boivin5Nicole Boivin6Nicole Boivin7Katerina Douka8Katerina Douka9Department of Archaeology, Max Planck Institute of Geoanthropology, Jena, GermanyInterdisciplinary Center for Archaeology and the Evolution of Human Behavior, Universidade do Algarve, Faro, PortugalDepartment of Evolutionary Anthropology, Faculty of Life Sciences, University of Vienna, Vienna, AustriaHuman Evolution and Archaeological Sciences (HEAS) Research Network, University of Vienna, Vienna, AustriaDepartment of Archaeology and Natural History, School of Culture, History & Language, Australian National University, Canberra, ACT, AustraliaDepartment of Archaeology, Max Planck Institute of Geoanthropology, Jena, GermanySchool of Social Science, The University of Queensland, Brisbane, QLD, AustraliaGriffith Sciences, Griffith University, Nathan, QLD, AustraliaDepartment of Evolutionary Anthropology, Faculty of Life Sciences, University of Vienna, Vienna, AustriaHuman Evolution and Archaeological Sciences (HEAS) Research Network, University of Vienna, Vienna, AustriaRecent advancements in biomolecular archaeology, such as stable isotope and ancient DNA research, have expanded our understanding of megafauna extinction processes and dynamics. The rise of palaeoproteomics, specifically Zooarchaeology by Mass Spectrometry (ZooMS), has added yet another method to this toolkit, as it can be used to taxonomically identify megafauna remains amongst highly fragmented bone assemblages. However, taxonomic identifications with ZooMS are reliant on the availability of collagen peptide markers for the regional fauna of interest. In the absence of a global reference database, most studies to date have been restricted to Eurasian contexts. Here, we report ZooMS peptide markers for three extinct Australian megafauna species: Zygomaturus trilobus, Palorchestes azael, and Protemnodon mamkurra. We show that these taxa can be differentiated from extant Australian fauna with these peptide markers. This foundational work represents an important step in establishing ZooMS as a method that can be used to identify new megafauna specimens in Australia’s highly fragmented fossil record and ultimately help resolve fundamental questions related to human–fauna–environment interactions.https://www.frontiersin.org/articles/10.3389/fmamm.2025.1564287/fullZooarchaeology by Mass SpectrometryDiprotodontidaePalorchestidaeMacropodidaelate Quaternary
spellingShingle Carli Peters
Carli Peters
Annette Oertle
Annette Oertle
Richard Gillespie
Nicole Boivin
Nicole Boivin
Nicole Boivin
Katerina Douka
Katerina Douka
Collagen peptide markers for three extinct Australian megafauna species
Frontiers in Mammal Science
Zooarchaeology by Mass Spectrometry
Diprotodontidae
Palorchestidae
Macropodidae
late Quaternary
title Collagen peptide markers for three extinct Australian megafauna species
title_full Collagen peptide markers for three extinct Australian megafauna species
title_fullStr Collagen peptide markers for three extinct Australian megafauna species
title_full_unstemmed Collagen peptide markers for three extinct Australian megafauna species
title_short Collagen peptide markers for three extinct Australian megafauna species
title_sort collagen peptide markers for three extinct australian megafauna species
topic Zooarchaeology by Mass Spectrometry
Diprotodontidae
Palorchestidae
Macropodidae
late Quaternary
url https://www.frontiersin.org/articles/10.3389/fmamm.2025.1564287/full
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