Navigating Through the Complications of Chronic Immunosuppression in Transplant Patients
The advent of organ transplantation has given hope to patients with end-stage organ failure. Allograft rejection is a transplant complication and remains a significant cause of transplant-related morbidity and mortality. Successful transplantation is achieved with immunosuppression, and the discover...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2022-10-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0940 |
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| _version_ | 1850147967064866816 |
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| author | Lemchukwu Chukwunonye Amaeshi |
| author_facet | Lemchukwu Chukwunonye Amaeshi |
| author_sort | Lemchukwu Chukwunonye Amaeshi |
| collection | DOAJ |
| description | The advent of organ transplantation has given hope to patients with end-stage organ failure. Allograft rejection is a transplant complication and remains a significant cause of transplant-related morbidity and mortality. Successful transplantation is achieved with immunosuppression, and the discovery of newer immunosuppressive agents has provided transplant physicians with more effective medications in preventing allograft rejection. On the flip side, long-term immunosuppression is fraught with complications such as predisposition to infections, malignancies, and cardiovascular diseases. The patient presented in the case report developed a transplant-related lymphoma many years after his kidney and pancreatic transplant. Primary care providers should be aware of these complications and educate their patients on measures to prevent some of them. |
| format | Article |
| id | doaj-art-96655ff2c09847a390cf461bb4c7bd54 |
| institution | OA Journals |
| issn | 2767-7664 |
| language | English |
| publishDate | 2022-10-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-96655ff2c09847a390cf461bb4c7bd542025-08-20T02:27:23ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642022-10-011810.7326/aimcc.2022.0940Navigating Through the Complications of Chronic Immunosuppression in Transplant PatientsLemchukwu Chukwunonye Amaeshi01Montefiore Medical Center, Bronx, New YorkThe advent of organ transplantation has given hope to patients with end-stage organ failure. Allograft rejection is a transplant complication and remains a significant cause of transplant-related morbidity and mortality. Successful transplantation is achieved with immunosuppression, and the discovery of newer immunosuppressive agents has provided transplant physicians with more effective medications in preventing allograft rejection. On the flip side, long-term immunosuppression is fraught with complications such as predisposition to infections, malignancies, and cardiovascular diseases. The patient presented in the case report developed a transplant-related lymphoma many years after his kidney and pancreatic transplant. Primary care providers should be aware of these complications and educate their patients on measures to prevent some of them.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0940 |
| spellingShingle | Lemchukwu Chukwunonye Amaeshi Navigating Through the Complications of Chronic Immunosuppression in Transplant Patients Annals of Internal Medicine: Clinical Cases |
| title | Navigating Through the Complications of Chronic Immunosuppression in Transplant Patients |
| title_full | Navigating Through the Complications of Chronic Immunosuppression in Transplant Patients |
| title_fullStr | Navigating Through the Complications of Chronic Immunosuppression in Transplant Patients |
| title_full_unstemmed | Navigating Through the Complications of Chronic Immunosuppression in Transplant Patients |
| title_short | Navigating Through the Complications of Chronic Immunosuppression in Transplant Patients |
| title_sort | navigating through the complications of chronic immunosuppression in transplant patients |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0940 |
| work_keys_str_mv | AT lemchukwuchukwunonyeamaeshi navigatingthroughthecomplicationsofchronicimmunosuppressionintransplantpatients |