Toehold Switch‐Based Approach for Engineering Acid‐Tolerance Modules to Enhance Production Robustness of Industrial E. coli Strains at Low pH

ABSTRACT Enhancing acid tolerance of industrial microorganisms is critical for improving fermentation efficiency and sustainability. This study presents a synthetic biology approach that employs toehold switch‐based acid‐tolerance modules to engineer acid‐tolerant strains. This toehold switch‐based...

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Bibliographic Details
Main Authors: Xin Zhang, Xiaofang Yan, Peng Liu, Haozheng Huang, Zhanglin Lin, Xiaofeng Yang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Microbial Biotechnology
Subjects:
Online Access:https://doi.org/10.1111/1751-7915.70175
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