Intra-articular drug injections in the combination treatment of rheumatic diseases
In clinical practice, intra-articular injections of glucocorticoids (GC) are widely used to treat chronic joint inflammatory diseases, osteoarthritis (OA), and extra-articular soft tissue involve-ment. GCs given to patients with chronic arthritis may rapidly suppress joint inflammatory changes and e...
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| Language: | Russian |
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IMA-PRESS LLC
2015-03-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/603 |
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| author | Yu. A. Olyunin |
| author_facet | Yu. A. Olyunin |
| author_sort | Yu. A. Olyunin |
| collection | DOAJ |
| description | In clinical practice, intra-articular injections of glucocorticoids (GC) are widely used to treat chronic joint inflammatory diseases, osteoarthritis (OA), and extra-articular soft tissue involve-ment. GCs given to patients with chronic arthritis may rapidly suppress joint inflammatory changes and ensure significant clinical improvements well before there is a benefit of prescribed disease-modifying antirheumatic drugs. According to the clinical features of disease, GCs may be used for systemic or local treatment in each specific case and a combination of these two treatments may be performed in some patients. In OA patents, the effect of intra-articular GC injections is less sustained than in those with joint inflammatory diseases and it persists for an average of about 3 weeks. Intra-articular hyaluronic acid is likely to be a more promising treatment for OA. It may also relieve pain considerably and improve joint functions. At the same time the highest effect was noted between weeks 5 and 13 after injection, but improvement also persisted after 14–26 weeks or longer in a number of cases. |
| format | Article |
| id | doaj-art-965ee9b015c24d82bd51266f998bee29 |
| institution | DOAJ |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2015-03-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-965ee9b015c24d82bd51266f998bee292025-08-20T02:56:01ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2015-03-0191788310.14412/1996-7012-2015-1-78-831901Intra-articular drug injections in the combination treatment of rheumatic diseasesYu. A. Olyunin0V.A. Nasonova Research Institute of RheumatologyIn clinical practice, intra-articular injections of glucocorticoids (GC) are widely used to treat chronic joint inflammatory diseases, osteoarthritis (OA), and extra-articular soft tissue involve-ment. GCs given to patients with chronic arthritis may rapidly suppress joint inflammatory changes and ensure significant clinical improvements well before there is a benefit of prescribed disease-modifying antirheumatic drugs. According to the clinical features of disease, GCs may be used for systemic or local treatment in each specific case and a combination of these two treatments may be performed in some patients. In OA patents, the effect of intra-articular GC injections is less sustained than in those with joint inflammatory diseases and it persists for an average of about 3 weeks. Intra-articular hyaluronic acid is likely to be a more promising treatment for OA. It may also relieve pain considerably and improve joint functions. At the same time the highest effect was noted between weeks 5 and 13 after injection, but improvement also persisted after 14–26 weeks or longer in a number of cases.https://mrj.ima-press.net/mrj/article/view/603rheumatic diseasesintra-articular injectionsglucocorticoidshyaluronic acid (hylan g-f20) |
| spellingShingle | Yu. A. Olyunin Intra-articular drug injections in the combination treatment of rheumatic diseases Современная ревматология rheumatic diseases intra-articular injections glucocorticoids hyaluronic acid (hylan g-f20) |
| title | Intra-articular drug injections in the combination treatment of rheumatic diseases |
| title_full | Intra-articular drug injections in the combination treatment of rheumatic diseases |
| title_fullStr | Intra-articular drug injections in the combination treatment of rheumatic diseases |
| title_full_unstemmed | Intra-articular drug injections in the combination treatment of rheumatic diseases |
| title_short | Intra-articular drug injections in the combination treatment of rheumatic diseases |
| title_sort | intra articular drug injections in the combination treatment of rheumatic diseases |
| topic | rheumatic diseases intra-articular injections glucocorticoids hyaluronic acid (hylan g-f20) |
| url | https://mrj.ima-press.net/mrj/article/view/603 |
| work_keys_str_mv | AT yuaolyunin intraarticulardruginjectionsinthecombinationtreatmentofrheumaticdiseases |