CS27109, A Selective Thyroid Hormone Receptor-β Agonist Alleviates Metabolic-Associated Fatty Liver Disease in Murine Models

CS27109, A Selective Thyroid Hormone Receptor-β Agonist Alleviates Metabolic-Associated Fatty Liver Disease in Murine Models

Background/Aim. Thyroid hormone receptor-β (THR-β) agonists play crucial roles in dyslipidemia and metabolic associated fatty liver disease (MAFLD). We developed a novel oral and liver-targeted THR-β agonist, CS27109, and evaluated its efficacy in the treatment of metabolic disorders. Materials and...

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Bibliographic Details
Main Authors: Shengjian Huang, Zhou Deng, Wei Wang, Guoqiang Liao, Yiru Zhao, Hua Zhong, Qian Zhang, Jing Liu, Xuhua Mao, Beizhong Chen, Desi Pan, You Zhou
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2023/4950597
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