Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers
Antioxidant and α-glucosidase inhibitiory active compounds of Cercis chinensis flowers were investigated with bio-assay guiding method. Ethyl acetate fraction (CLEa) and n-butanol fraction (CLBu) exhibited antioxidant and α-glucosidase inhibitiory activity in vitro, and the corresponding active frac...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2020-12-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453020301312 |
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| author | Juanjuan Zhang Li Zhou Lili Cui Zhenhua Liu Jinfeng Wei Wenyi Kang |
| author_facet | Juanjuan Zhang Li Zhou Lili Cui Zhenhua Liu Jinfeng Wei Wenyi Kang |
| author_sort | Juanjuan Zhang |
| collection | DOAJ |
| description | Antioxidant and α-glucosidase inhibitiory active compounds of Cercis chinensis flowers were investigated with bio-assay guiding method. Ethyl acetate fraction (CLEa) and n-butanol fraction (CLBu) exhibited antioxidant and α-glucosidase inhibitiory activity in vitro, and the corresponding active fractions, EaFr.3, EaFr.5 and BuFr.1, exhibited higher antioxidant and α-glucosidase inhibitiory activity than those of other fractions. Eight compounds, ethyl gallate (1), stearic acid (2), docosanoic acid (3), 5α-stigmast-9(11)-en-3β-ol (4), kaempferol-3-O-α-rhamnopyranoside (5), vanillic acid (6), fisetin (7), and β-sitosterol (8), were isolated and identified from CLEa and CLBu. Ethyl gallate shown the highest antioxidant activity by scavenging DPPH radical and reducing ferric compared. Docosanoic acid and vanillic acid shown stronger α-glucosidase inhibitory activity than that of acarbose. |
| format | Article |
| id | doaj-art-9658eaae442b49ab8a3bec0353bdbcf7 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-9658eaae442b49ab8a3bec0353bdbcf72025-02-03T06:34:59ZengTsinghua University PressFood Science and Human Wellness2213-45302020-12-0194313319Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowersJuanjuan Zhang0Li Zhou1Lili Cui2Zhenhua Liu3Jinfeng Wei4Wenyi Kang5National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Zhengzhou City Key Laboratory of Medicinal Resources Research, Huanghe Science and Technology College, Zhengzhou, 450063, ChinaNational R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Kaifeng Key Laboratory of Functional Components in Health Food, Kaifeng, 475004, China; Joint International Research Laboratory of Food & Medicine Resource Function, Henan Province, Kaifeng, 475004, ChinaNational R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Kaifeng Key Laboratory of Functional Components in Health Food, Kaifeng, 475004, China; Joint International Research Laboratory of Food & Medicine Resource Function, Henan Province, Kaifeng, 475004, ChinaNational R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Joint International Research Laboratory of Food & Medicine Resource Function, Henan Province, Kaifeng, 475004, ChinaNational R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Kaifeng Key Laboratory of Functional Components in Health Food, Kaifeng, 475004, China; Joint International Research Laboratory of Food & Medicine Resource Function, Henan Province, Kaifeng, 475004, China; Minsheng College, Henan University, Kaifeng, Henan, 475004, China; Corresponding author at: National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China.National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China; Kaifeng Key Laboratory of Functional Components in Health Food, Kaifeng, 475004, China; Joint International Research Laboratory of Food & Medicine Resource Function, Henan Province, Kaifeng, 475004, China; Corresponding author at: National R & D Center for Edible Fungus Processing Technology, Henan University, Kaifeng, 475004, China.Antioxidant and α-glucosidase inhibitiory active compounds of Cercis chinensis flowers were investigated with bio-assay guiding method. Ethyl acetate fraction (CLEa) and n-butanol fraction (CLBu) exhibited antioxidant and α-glucosidase inhibitiory activity in vitro, and the corresponding active fractions, EaFr.3, EaFr.5 and BuFr.1, exhibited higher antioxidant and α-glucosidase inhibitiory activity than those of other fractions. Eight compounds, ethyl gallate (1), stearic acid (2), docosanoic acid (3), 5α-stigmast-9(11)-en-3β-ol (4), kaempferol-3-O-α-rhamnopyranoside (5), vanillic acid (6), fisetin (7), and β-sitosterol (8), were isolated and identified from CLEa and CLBu. Ethyl gallate shown the highest antioxidant activity by scavenging DPPH radical and reducing ferric compared. Docosanoic acid and vanillic acid shown stronger α-glucosidase inhibitory activity than that of acarbose.http://www.sciencedirect.com/science/article/pii/S2213453020301312Antioxidative activityCercis chinensis bungeChemical componentα-glucosidase |
| spellingShingle | Juanjuan Zhang Li Zhou Lili Cui Zhenhua Liu Jinfeng Wei Wenyi Kang Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers Food Science and Human Wellness Antioxidative activity Cercis chinensis bunge Chemical component α-glucosidase |
| title | Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers |
| title_full | Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers |
| title_fullStr | Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers |
| title_full_unstemmed | Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers |
| title_short | Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers |
| title_sort | antioxidant and α glucosidase inhibitiory activity of cercis chinensis flowers |
| topic | Antioxidative activity Cercis chinensis bunge Chemical component α-glucosidase |
| url | http://www.sciencedirect.com/science/article/pii/S2213453020301312 |
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