Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide
Three series of new N-(α–naphthyl-2-(aryl hydrazono)-3-oxo butanamide, N-(6-chloro) benzothiazol-2-yl)-2-(aryl hydrazono)-3- oxo butanamide and N-(6-methyl) benzothiazol-2-yl)-2-(aryl hydrazono)-3- oxo butanamide were synthesized in two steps derived from α-naphthyl amine, 2-aminobenzothiazole....
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University of Baghdad, College of Science for Women
2024-10-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11923 |
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| author | Luma S. Ahamed Zena G. Al-Rekabi |
| author_facet | Luma S. Ahamed Zena G. Al-Rekabi |
| author_sort | Luma S. Ahamed |
| collection | DOAJ |
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Three series of new N-(α–naphthyl-2-(aryl hydrazono)-3-oxo butanamide, N-(6-chloro) benzothiazol-2-yl)-2-(aryl hydrazono)-3- oxo butanamide and N-(6-methyl) benzothiazol-2-yl)-2-(aryl hydrazono)-3- oxo butanamide were synthesized in two steps derived from α-naphthyl amine, 2-aminobenzothiazole. : The first step was involved the reaction of different fused aromatic amines (α-naphthyl amine, 6-chloro-2-aminobenzothiazole and 6-methyl-2- aminobenzothiazole) with methyl acetoacetate at (160-170) 0C by using modern method to provide greatly improved yields. In the second step arenediazonium chloride was added to [3-oxo-butanamide derivatives] in basic solution at (0-5) 0C to get ten new dyes of aryl hydrazono derivatives. These synthesized compounds were characterized by FT-IR, 13C-NMR, 1H-NMR, UV-Visible spectroscopy, and by measuring their melting points, and solubility.
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| format | Article |
| id | doaj-art-96551840b540454da63ca277dafbfd0f |
| institution | Kabale University |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | University of Baghdad, College of Science for Women |
| record_format | Article |
| series | مجلة بغداد للعلوم |
| spelling | doaj-art-96551840b540454da63ca277dafbfd0f2025-08-20T03:34:57ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862024-10-017110.21123/bsj.2010.11923Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide Luma S. AhamedZena G. Al-Rekabi Three series of new N-(α–naphthyl-2-(aryl hydrazono)-3-oxo butanamide, N-(6-chloro) benzothiazol-2-yl)-2-(aryl hydrazono)-3- oxo butanamide and N-(6-methyl) benzothiazol-2-yl)-2-(aryl hydrazono)-3- oxo butanamide were synthesized in two steps derived from α-naphthyl amine, 2-aminobenzothiazole. : The first step was involved the reaction of different fused aromatic amines (α-naphthyl amine, 6-chloro-2-aminobenzothiazole and 6-methyl-2- aminobenzothiazole) with methyl acetoacetate at (160-170) 0C by using modern method to provide greatly improved yields. In the second step arenediazonium chloride was added to [3-oxo-butanamide derivatives] in basic solution at (0-5) 0C to get ten new dyes of aryl hydrazono derivatives. These synthesized compounds were characterized by FT-IR, 13C-NMR, 1H-NMR, UV-Visible spectroscopy, and by measuring their melting points, and solubility. https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11923benzothiazolide, Synthesis, aryl hydrazone, α-naphthalide |
| spellingShingle | Luma S. Ahamed Zena G. Al-Rekabi Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide مجلة بغداد للعلوم benzothiazolide, Synthesis, aryl hydrazone, α-naphthalide |
| title | Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide |
| title_full | Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide |
| title_fullStr | Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide |
| title_full_unstemmed | Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide |
| title_short | Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide |
| title_sort | synthesis of aryl hydrazone derivatives for α naphthalide and benzothiazolide |
| topic | benzothiazolide, Synthesis, aryl hydrazone, α-naphthalide |
| url | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11923 |
| work_keys_str_mv | AT lumasahamed synthesisofarylhydrazonederivativesforanaphthalideandbenzothiazolide AT zenagalrekabi synthesisofarylhydrazonederivativesforanaphthalideandbenzothiazolide |