Cartilage-Specific <sup>18</sup>F-NaF Uptake in Rat Models: A Multimodal In Vitro and Ex Vitro Comparative Study with <sup>99m</sup>Tc-MDP

Cartilage-Specific <sup>18</sup>F-NaF Uptake in Rat Models: A Multimodal In Vitro and Ex Vitro Comparative Study with <sup>99m</sup>Tc-MDP

<b>Background:</b> <sup>18</sup>F-NaF and <sup>99m</sup>Tc-MDP are widely used bone imaging tracers, but their comparative uptake in bone versus cartilage is unclear. This study aimed to directly compare these patterns in rats to guide musculoskeletal molecular im...

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Bibliographic Details
Main Authors: Qingxiao Li, Jianpeng Gao, Yiqun Wang, Yaoyao Song, Liwei Liu, Cong Zhang, Ming Li, Haodan Dang, Jiahe Tian
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
<sup>18</sup>F-NaF
<sup>99m</sup>Tc-MDP
bone imaging
calcification
multimodal imaging
early osteoarthritis
Online Access:https://www.mdpi.com/2227-9059/13/7/1540
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