The cell autonomous and non-autonomous roles of itaconate in immune response
Itaconate which is discovered as a mammalian metabolite possessing antimicrobial and immunoregulatory activity has attracted much attention in the field of immunometabolism. Itaconate is synthesized by myeloid cells under conditions of pathogen infection and sterile inflammation. In addition to regu...
Saved in:
Main Authors: | Chao Chen, Xinjian Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
|
Series: | Cell Insight |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772892724000798 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Lack of Hypoxia Inducible Factor-1α Influences on Macrophages Ability to Deal with Leishmania braziliensis In Vitro and Affects Pathology In Vivo
by: Rodrigo C.O. Sanches, et al.
Published: (2025-05-01) -
4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain
by: Yu-Zhen Tang, et al.
Published: (2025-01-01) -
IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury
by: Liwu Zeng, et al.
Published: (2025-02-01) -
Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine
by: Vijay Kumar
Published: (2025-01-01) -
Simple hypertrophic tonsils have more active innate immune and inflammatory responses than hypertrophic tonsils with recurrent inflammation in children
by: Qun Huang, et al.
Published: (2020-06-01)