Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.

Alzheimer's disease and related dementias (ADRD) are a growing global health concern, with burdens projected to expand rapidly in the coming decades. Since cognitive decline typically precedes ADRD, it is crucial to identify interventions that may help slow cognitive decline and reduce ADRD ris...

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Main Authors: Janet Jock, Erika T Beidelman, Meredith Phillips, Lindsay C Kobayashi, Xiwei Chen, Stephen Tollman, Chodziwadziwa Whiteson Kabudula, Darina T Bassil, Ryan Wagner, Lisa Berkman, Molly Rosenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326321
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author Janet Jock
Erika T Beidelman
Meredith Phillips
Lindsay C Kobayashi
Xiwei Chen
Stephen Tollman
Chodziwadziwa Whiteson Kabudula
Darina T Bassil
Ryan Wagner
Lisa Berkman
Molly Rosenberg
author_facet Janet Jock
Erika T Beidelman
Meredith Phillips
Lindsay C Kobayashi
Xiwei Chen
Stephen Tollman
Chodziwadziwa Whiteson Kabudula
Darina T Bassil
Ryan Wagner
Lisa Berkman
Molly Rosenberg
author_sort Janet Jock
collection DOAJ
description Alzheimer's disease and related dementias (ADRD) are a growing global health concern, with burdens projected to expand rapidly in the coming decades. Since cognitive decline typically precedes ADRD, it is crucial to identify interventions that may help slow cognitive decline and reduce ADRD risk. We used a quasi-experimental design, exploiting exogenous expansions of South Africa's Older Persons Grant for men, to estimate its impact on memory decline and ADRD risk in the rural Mpumalanga province of South Africa. We found that expanded pension eligibility was associated with slower memory decline for men who were eligible to receive the pension 5 years earlier [β = 0.027 SD, 95% CI = 0.023, 0.031], as well as for men who were eligible to receive the pension 1-4 years earlier [β = 0.009 SD, 95% CI = 0.004, 0.013]. We also found a 5.2 percentage point lower probability of dementia for men who were eligible for pension 5 years earlier [95% CI = -0.062, -0.032] and a 4.8 percentage point lower probability of dementia for men who became eligible to receive pension 1-4 years earlier [95% CI = -0.062, -0.032]. These findings demonstrate that beyond the policy intent of cash transfers to strengthen individual and household livelihoods, an important further benefit lies in promoting healthy cognitive aging in low- and middle- income countries.
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spelling doaj-art-9645eb090a284aba97031e709a2516bf2025-08-20T03:29:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01206e032632110.1371/journal.pone.0326321Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.Janet JockErika T BeidelmanMeredith PhillipsLindsay C KobayashiXiwei ChenStephen TollmanChodziwadziwa Whiteson KabudulaDarina T BassilRyan WagnerLisa BerkmanMolly RosenbergAlzheimer's disease and related dementias (ADRD) are a growing global health concern, with burdens projected to expand rapidly in the coming decades. Since cognitive decline typically precedes ADRD, it is crucial to identify interventions that may help slow cognitive decline and reduce ADRD risk. We used a quasi-experimental design, exploiting exogenous expansions of South Africa's Older Persons Grant for men, to estimate its impact on memory decline and ADRD risk in the rural Mpumalanga province of South Africa. We found that expanded pension eligibility was associated with slower memory decline for men who were eligible to receive the pension 5 years earlier [β = 0.027 SD, 95% CI = 0.023, 0.031], as well as for men who were eligible to receive the pension 1-4 years earlier [β = 0.009 SD, 95% CI = 0.004, 0.013]. We also found a 5.2 percentage point lower probability of dementia for men who were eligible for pension 5 years earlier [95% CI = -0.062, -0.032] and a 4.8 percentage point lower probability of dementia for men who became eligible to receive pension 1-4 years earlier [95% CI = -0.062, -0.032]. These findings demonstrate that beyond the policy intent of cash transfers to strengthen individual and household livelihoods, an important further benefit lies in promoting healthy cognitive aging in low- and middle- income countries.https://doi.org/10.1371/journal.pone.0326321
spellingShingle Janet Jock
Erika T Beidelman
Meredith Phillips
Lindsay C Kobayashi
Xiwei Chen
Stephen Tollman
Chodziwadziwa Whiteson Kabudula
Darina T Bassil
Ryan Wagner
Lisa Berkman
Molly Rosenberg
Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.
PLoS ONE
title Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.
title_full Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.
title_fullStr Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.
title_full_unstemmed Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.
title_short Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.
title_sort effects of pension eligibility expansion on men s memory decline and dementia probability findings from the haalsi cohort in rural south africa 2014 2021
url https://doi.org/10.1371/journal.pone.0326321
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