Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma.

Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma.

<h4>Background & aims</h4>Insulin-like growth factor, (IGF)-1, is produced mainly by the liver and plays important roles in promoting growth and regulating metabolism. Previous study reported that development of hepatocellular carcinoma (HCC) was accompanied by a significant reductio...

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Main Authors: Tzu-Min Hung, Cheng-Maw Ho, Yen-Chun Liu, Jia-Ling Lee, Yow-Rong Liao, Yao-Ming Wu, Ming-Chih Ho, Chien-Hung Chen, Hong-Shiee Lai, Po-Huang Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089446&type=printable
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