Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoring
Aim of investigation. To study antisecretory activity of the first dose of esomeprazole (20 or 40 mg) (Emanera®, «KRKA», Slovenia) by long-term intragastric pH monitoring. Material and methods. Long-term intragastric pH monitoring was carried out in 20 patients with acidrelated diseases by «Gastrosk...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2016-08-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/58 |
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| author | S. A. Kurilovich Ye. A. Chekalina A. V. Belkovets L. V. Scherbakova |
| author_facet | S. A. Kurilovich Ye. A. Chekalina A. V. Belkovets L. V. Scherbakova |
| author_sort | S. A. Kurilovich |
| collection | DOAJ |
| description | Aim of investigation. To study antisecretory activity of the first dose of esomeprazole (20 or 40 mg) (Emanera®, «KRKA», Slovenia) by long-term intragastric pH monitoring. Material and methods. Long-term intragastric pH monitoring was carried out in 20 patients with acidrelated diseases by «Gastroskan-24» device («IstokSistema», Fryazino, Russia). In the first 24 hours patients received no antisecretory agents, in the morning of the next day - they received esomeprazole 20 or 40 mg orally 30 min. prior to the breakfast. Median pH, both time with various pH values and area under pH distribution curve, percent of this time with values from 1,0 to 10,0 per day before and after esomeprazole administration were estimated. The respective scores were compared, using Wilcoxon criterion. Differences were considered to be significant at р |
| format | Article |
| id | doaj-art-962adb086a5240899a7c5a922708c639 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-962adb086a5240899a7c5a922708c6392025-02-10T16:14:34ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732016-08-01263334010.22416/1382-4376-2016-26-3-33-4058Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoringS. A. Kurilovich0Ye. A. Chekalina1A. V. Belkovets2L. V. Scherbakova3Federal State Budgetary Institution «Institution of Internal and Preventive Medicine» ; State educational government-financed institution of higher professional education «Novosibirsk state medical university»Federal State Budgetary Institution «Institution of Internal and Preventive Medicine»Federal State Budgetary Institution «Institution of Internal and Preventive Medicine»Federal State Budgetary Institution «Institution of Internal and Preventive Medicine»Aim of investigation. To study antisecretory activity of the first dose of esomeprazole (20 or 40 mg) (Emanera®, «KRKA», Slovenia) by long-term intragastric pH monitoring. Material and methods. Long-term intragastric pH monitoring was carried out in 20 patients with acidrelated diseases by «Gastroskan-24» device («IstokSistema», Fryazino, Russia). In the first 24 hours patients received no antisecretory agents, in the morning of the next day - they received esomeprazole 20 or 40 mg orally 30 min. prior to the breakfast. Median pH, both time with various pH values and area under pH distribution curve, percent of this time with values from 1,0 to 10,0 per day before and after esomeprazole administration were estimated. The respective scores were compared, using Wilcoxon criterion. Differences were considered to be significant at рhttps://www.gastro-j.ru/jour/article/view/58кислотозависимые заболеваниядлительный мониторинг интрагастрального рнэзомепразолэманера® |
| spellingShingle | S. A. Kurilovich Ye. A. Chekalina A. V. Belkovets L. V. Scherbakova Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoring Российский журнал гастроэнтерологии, гепатологии, колопроктологии кислотозависимые заболевания длительный мониторинг интрагастрального рн эзомепразол эманера® |
| title | Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoring |
| title_full | Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoring |
| title_fullStr | Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoring |
| title_full_unstemmed | Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoring |
| title_short | Dose-dependent esomeprasole antisecretory effect: results of long-term intragastric pH monitoring |
| title_sort | dose dependent esomeprasole antisecretory effect results of long term intragastric ph monitoring |
| topic | кислотозависимые заболевания длительный мониторинг интрагастрального рн эзомепразол эманера® |
| url | https://www.gastro-j.ru/jour/article/view/58 |
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