ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing Complication
To date, eleven cases of irreversible neurological defects in T- ALL patients treated with nelarabine have been described in the last 4 years, seven of these after stem cell transplantation (SCT) for T Lymphoblastic Lymphoma (T-LBL). Most of patients had an unfavorable outcome or irreversible damage...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2015-02-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/2136 |
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| author | Maria Chiara Tisi Giuseppe Ausoni Maria Gabriella Vita Tommaso Tartaglione Mario Balducci Luca Laurenti Patrizia Chiusolo Stefan Hohaus Simona Sica |
| author_facet | Maria Chiara Tisi Giuseppe Ausoni Maria Gabriella Vita Tommaso Tartaglione Mario Balducci Luca Laurenti Patrizia Chiusolo Stefan Hohaus Simona Sica |
| author_sort | Maria Chiara Tisi |
| collection | DOAJ |
| description | To date, eleven cases of irreversible neurological defects in T- ALL patients treated with nelarabine have been described in the last 4 years, seven of these after stem cell transplantation (SCT) for T Lymphoblastic Lymphoma (T-LBL). Most of patients had an unfavorable outcome or irreversible damage.
We report the case of a 41-year-old woman suffering from T-LBL who presented severe but reversible myelopathy after nelarabine based treatment and mediastinum radiotherapy, and we perform a review of literature. |
| format | Article |
| id | doaj-art-960d7c63a8de4029865e1b57a09a0fe0 |
| institution | OA Journals |
| issn | 2035-3006 |
| language | English |
| publishDate | 2015-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-960d7c63a8de4029865e1b57a09a0fe02025-08-20T02:08:34ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062015-02-0171e2015025e201502510.4084/mjhid.2015.0251548ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing ComplicationMaria Chiara Tisi0Giuseppe Ausoni1Maria Gabriella Vita2Tommaso Tartaglione3Mario Balducci4Luca Laurenti5Patrizia Chiusolo6Stefan Hohaus7Simona Sica8Institute of Hematology, Catholic University S. Cuore, RomeInstitute of Hematology, Catholic University S. Cuore, RomeInstitute of Neurology, Catholic University S. Cuore, RomeInstitute of Radiology, Catholic University S. Cuore, RomeInstitute of Radiation Oncology, Catholic University S. Cuore, RomeInstitute of Hematology, Catholic University S. Cuore, RomeInstitute of Hematology, Catholic University S. Cuore, RomeInstitute of Hematology, Catholic University S. Cuore, Romestefan.hohaus@rm.unicatt.itTo date, eleven cases of irreversible neurological defects in T- ALL patients treated with nelarabine have been described in the last 4 years, seven of these after stem cell transplantation (SCT) for T Lymphoblastic Lymphoma (T-LBL). Most of patients had an unfavorable outcome or irreversible damage. We report the case of a 41-year-old woman suffering from T-LBL who presented severe but reversible myelopathy after nelarabine based treatment and mediastinum radiotherapy, and we perform a review of literature.http://www.mjhid.org/index.php/mjhid/article/view/2136T Lymphoblastic Lymphoma, Nelarabine, Myelopathy |
| spellingShingle | Maria Chiara Tisi Giuseppe Ausoni Maria Gabriella Vita Tommaso Tartaglione Mario Balducci Luca Laurenti Patrizia Chiusolo Stefan Hohaus Simona Sica ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing Complication Mediterranean Journal of Hematology and Infectious Diseases T Lymphoblastic Lymphoma, Nelarabine, Myelopathy |
| title | ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing Complication |
| title_full | ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing Complication |
| title_fullStr | ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing Complication |
| title_full_unstemmed | ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing Complication |
| title_short | ClinicaI Reversible Myelopathy in T-Cell Lymphoblastic Lymphoma Treated with Nelarabine and Radiotherapy: Report of a Case and Review of Literature of an Increasing Complication |
| title_sort | clinicai reversible myelopathy in t cell lymphoblastic lymphoma treated with nelarabine and radiotherapy report of a case and review of literature of an increasing complication |
| topic | T Lymphoblastic Lymphoma, Nelarabine, Myelopathy |
| url | http://www.mjhid.org/index.php/mjhid/article/view/2136 |
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