ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images
Abstract Hematoxylin and eosin (H&E) is a common and inexpensive histopathology assay. Though widely used and information-rich, it cannot directly inform about specific molecular markers, which require additional experiments to assess. To address this gap, we present ROSIE, a deep-learning frame...
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| Main Authors: | Eric Wu, Matthew Bieniosek, Zhenqin Wu, Nitya Thakkar, Gregory W. Charville, Ahmad Makky, Christian M. Schürch, Jeroen R. Huyghe, Ulrike Peters, Christopher I. Li, Li Li, Hannah Giba, Vivek Behera, Arjun Raman, Alexandro E. Trevino, Aaron T. Mayer, James Zou |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62346-0 |
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