Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?
Mixed invasive mold infections (MIMIs) are considered rare. We present a case of fatal aspergillosis and mucormycosis in an elderly host with history of chronic lymphocytic leukemia (CLL) and potential mold exposures. Notably, he had no classic risk factors for IMI other than high-dose corticosteroi...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2020/8812528 |
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| author | Maria Tsikala-Vafea Weibiao Cao Adam J. Olszewski John E. Donahue Dimitrios Farmakiotis |
| author_facet | Maria Tsikala-Vafea Weibiao Cao Adam J. Olszewski John E. Donahue Dimitrios Farmakiotis |
| author_sort | Maria Tsikala-Vafea |
| collection | DOAJ |
| description | Mixed invasive mold infections (MIMIs) are considered rare. We present a case of fatal aspergillosis and mucormycosis in an elderly host with history of chronic lymphocytic leukemia (CLL) and potential mold exposures. Notably, he had no classic risk factors for IMI other than high-dose corticosteroids, which may be an important risk factor for (M)IMI, based on the current and previous reports. There is an urgent need for studies on the “net state of immunosuppression,” environmental exposure as risk factors for (M)IMIs, and noninvasive fungal diagnostics. |
| format | Article |
| id | doaj-art-95fb6efe03064c699184624ab62649c9 |
| institution | OA Journals |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-95fb6efe03064c699184624ab62649c92025-08-20T02:10:16ZengWileyCase Reports in Infectious Diseases2090-66252090-66332020-01-01202010.1155/2020/88125288812528Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?Maria Tsikala-Vafea0Weibiao Cao1Adam J. Olszewski2John E. Donahue3Dimitrios Farmakiotis4Division of Infectious Diseases, Department of Internal Medicine, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USADepartment of Pathology, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USADivision of Hematology-Oncology, Department of Internal Medicine, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USADepartment of Pathology, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USADivision of Infectious Diseases, Department of Internal Medicine, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USAMixed invasive mold infections (MIMIs) are considered rare. We present a case of fatal aspergillosis and mucormycosis in an elderly host with history of chronic lymphocytic leukemia (CLL) and potential mold exposures. Notably, he had no classic risk factors for IMI other than high-dose corticosteroids, which may be an important risk factor for (M)IMI, based on the current and previous reports. There is an urgent need for studies on the “net state of immunosuppression,” environmental exposure as risk factors for (M)IMIs, and noninvasive fungal diagnostics.http://dx.doi.org/10.1155/2020/8812528 |
| spellingShingle | Maria Tsikala-Vafea Weibiao Cao Adam J. Olszewski John E. Donahue Dimitrios Farmakiotis Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections? Case Reports in Infectious Diseases |
| title | Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections? |
| title_full | Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections? |
| title_fullStr | Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections? |
| title_full_unstemmed | Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections? |
| title_short | Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections? |
| title_sort | fatal mucormycosis and aspergillosis in an atypical host what do we know about mixed invasive mold infections |
| url | http://dx.doi.org/10.1155/2020/8812528 |
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