Methylprednisolone Administration Following Spinal Cord Injury Reduces Aquaporin 4 Expression and Exacerbates Edema

Methylprednisolone Administration Following Spinal Cord Injury Reduces Aquaporin 4 Expression and Exacerbates Edema

Spinal cord injury (SCI) is an incapacitating condition that affects motor, sensory, and autonomic functions. Since 1990, the only treatment administered in the acute phase of SCI has been methylprednisolone (MP), a synthetic corticosteroid that has anti-inflammatory effects; however, its efficacy r...

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Bibliographic Details
Main Authors: Eibar Ernesto Cabrera-Aldana, Fernando Ruelas, Cristina Aranda, Ruth Rincon-Heredia, Angelina Martínez-Cruz, Alejandro Reyes-Sánchez, Gabriel Guizar-Sahagún, Luis B. Tovar-y-Romo
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2017/4792932
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