Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive study

Abstract Objective To determine the age-specific distribution of serum calcium levels in the Xing’an League population and assess the applicability of current national standards. Methods Data were collected from 3000 healthy individuals across different age groups in the Xing’an League, stratified b...

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Main Authors: Haiyan Hu, Wulan Wang, Zenan Chang, Siyu Wang, Yulong Zhang, Lili Zou, Wanying Song, Jing Zhang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Health, Population and Nutrition
Subjects:
Online Access:https://doi.org/10.1186/s41043-025-00954-8
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author Haiyan Hu
Wulan Wang
Zenan Chang
Siyu Wang
Yulong Zhang
Lili Zou
Wanying Song
Jing Zhang
author_facet Haiyan Hu
Wulan Wang
Zenan Chang
Siyu Wang
Yulong Zhang
Lili Zou
Wanying Song
Jing Zhang
author_sort Haiyan Hu
collection DOAJ
description Abstract Objective To determine the age-specific distribution of serum calcium levels in the Xing’an League population and assess the applicability of current national standards. Methods Data were collected from 3000 healthy individuals across different age groups in the Xing’an League, stratified by sex and age. Serum calcium levels were measured, and statistical methods were used to analyse sex- and age-related differences. The relevance of the current Chinese Health Industry Standard reference intervals for serum calcium was evaluated, and age-related trends were assessed. Results Significant differences in serum calcium levels were found between sexes and across age groups. The current national reference intervals did not adequately capture the age- and region-specific characteristics of serum calcium levels in the Xing’an League population, highlighting the need for localized evaluation criteria. Conclusion The study demonstrates the impact of sex and age on serum calcium levels and emphasises the importance of recognising regional variations. The findings provide a scientific basis for enhancing disease prevention and developing personalised treatment strategies to address regional disparities in clinical practice.
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series Journal of Health, Population and Nutrition
spelling doaj-art-95ed38fcd01a4c729e2267a37fe239fd2025-08-20T03:22:50ZengBMCJournal of Health, Population and Nutrition2072-13152025-06-014411710.1186/s41043-025-00954-8Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive studyHaiyan Hu0Wulan Wang1Zenan Chang2Siyu Wang3Yulong Zhang4Lili Zou5Wanying Song6Jing Zhang7The Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionThe Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionThe Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionThe Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionThe Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionThe Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionThe Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionThe Clinical Laboratory Department of the Xing ‘an League People’s Hospital of Inner Mongolia Autonomous RegionAbstract Objective To determine the age-specific distribution of serum calcium levels in the Xing’an League population and assess the applicability of current national standards. Methods Data were collected from 3000 healthy individuals across different age groups in the Xing’an League, stratified by sex and age. Serum calcium levels were measured, and statistical methods were used to analyse sex- and age-related differences. The relevance of the current Chinese Health Industry Standard reference intervals for serum calcium was evaluated, and age-related trends were assessed. Results Significant differences in serum calcium levels were found between sexes and across age groups. The current national reference intervals did not adequately capture the age- and region-specific characteristics of serum calcium levels in the Xing’an League population, highlighting the need for localized evaluation criteria. Conclusion The study demonstrates the impact of sex and age on serum calcium levels and emphasises the importance of recognising regional variations. The findings provide a scientific basis for enhancing disease prevention and developing personalised treatment strategies to address regional disparities in clinical practice.https://doi.org/10.1186/s41043-025-00954-8Serum biochemistryCalcium metabolismRegional health referencePopulation-based studyLaboratory reference values
spellingShingle Haiyan Hu
Wulan Wang
Zenan Chang
Siyu Wang
Yulong Zhang
Lili Zou
Wanying Song
Jing Zhang
Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive study
Journal of Health, Population and Nutrition
Serum biochemistry
Calcium metabolism
Regional health reference
Population-based study
Laboratory reference values
title Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive study
title_full Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive study
title_fullStr Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive study
title_full_unstemmed Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive study
title_short Age-specific serum calcium levels in healthy individuals from the Xing’an League: a descriptive study
title_sort age specific serum calcium levels in healthy individuals from the xing an league a descriptive study
topic Serum biochemistry
Calcium metabolism
Regional health reference
Population-based study
Laboratory reference values
url https://doi.org/10.1186/s41043-025-00954-8
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