Pruritus and Atopic Dermatitis: from Etiological Features to Management

Pruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was co...

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Main Authors: Nikolay N. Murashkin, Leonid A. Opryatin, Roman V. Epishev, Alexander I. Materikin, Eduard T. Ambarchian, Roman A. Ivanov, Dmitriy V. Fedorov, Daria S. Kukoleva
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2020-12-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/2508
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author Nikolay N. Murashkin
Leonid A. Opryatin
Roman V. Epishev
Alexander I. Materikin
Eduard T. Ambarchian
Roman A. Ivanov
Dmitriy V. Fedorov
Daria S. Kukoleva
author_facet Nikolay N. Murashkin
Leonid A. Opryatin
Roman V. Epishev
Alexander I. Materikin
Eduard T. Ambarchian
Roman A. Ivanov
Dmitriy V. Fedorov
Daria S. Kukoleva
author_sort Nikolay N. Murashkin
collection DOAJ
description Pruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was confounded, as well as data on immune system involvement in its maintenance was given. This article presents current data on differential approaches to pruritus management depending on its etiopathogenetic characteristics. The role of dermocosmetics in restoration of the skin barrier as the first stage prevention of pruritus in atopic dermatitis was considered. The results of clinical studies showing efficacy of topical agents (innovative component with anti-pruritic action — STIMU-TEX) application are presented.
format Article
id doaj-art-95ea216c4ddc440d95667b7c82e63da3
institution Kabale University
issn 1682-5527
1682-5535
language English
publishDate 2020-12-01
publisher "Paediatrician" Publishers LLC
record_format Article
series Вопросы современной педиатрии
spelling doaj-art-95ea216c4ddc440d95667b7c82e63da32025-08-20T03:59:53Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352020-12-0119646847610.15690/vsp.v19i6.21511916Pruritus and Atopic Dermatitis: from Etiological Features to ManagementNikolay N. Murashkin0Leonid A. Opryatin1Roman V. Epishev2Alexander I. Materikin3Eduard T. Ambarchian4Roman A. Ivanov5Dmitriy V. Fedorov6Daria S. Kukoleva7National Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential Affairs; Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”National Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthPruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was confounded, as well as data on immune system involvement in its maintenance was given. This article presents current data on differential approaches to pruritus management depending on its etiopathogenetic characteristics. The role of dermocosmetics in restoration of the skin barrier as the first stage prevention of pruritus in atopic dermatitis was considered. The results of clinical studies showing efficacy of topical agents (innovative component with anti-pruritic action — STIMU-TEX) application are presented.https://vsp.spr-journal.ru/jour/article/view/2508pruritusatopic dermatitisskin barrierdermocosmeticsemollient plus
spellingShingle Nikolay N. Murashkin
Leonid A. Opryatin
Roman V. Epishev
Alexander I. Materikin
Eduard T. Ambarchian
Roman A. Ivanov
Dmitriy V. Fedorov
Daria S. Kukoleva
Pruritus and Atopic Dermatitis: from Etiological Features to Management
Вопросы современной педиатрии
pruritus
atopic dermatitis
skin barrier
dermocosmetics
emollient plus
title Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_full Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_fullStr Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_full_unstemmed Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_short Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_sort pruritus and atopic dermatitis from etiological features to management
topic pruritus
atopic dermatitis
skin barrier
dermocosmetics
emollient plus
url https://vsp.spr-journal.ru/jour/article/view/2508
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