Characterization of the nigroestriatal system in a sample of patients with amyotrophic lateral sclerosis

Characterization of the nigroestriatal system in a sample of patients with amyotrophic lateral sclerosis

Background The coexistence of amyotrophic lateral sclerosis (ALS) with clinical forms of Parkinson disease (PD), although uncommon, is found to a greater degree than one would expect by chance. The pathological mechanisms of ALS and PD are still not fully understood, and the coexistence o...

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Main Authors: Claudio Alejandro Jimenez Monsalve, Luis Henrique Tieppo Fornari, Neivo da Silva Júnior, Douglas Tomio Nakata, Eurípedes Gomes de Carvalho Neto, Francisco Tellechea Rotta, Carlos Roberto de Mello Rieder
Format: Article
Language:English
Published: Thieme Revinter Publicações 2022-08-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Amyotrophic Lateral Sclerosis
Parkinson Disease
Dopamine Plasma Membrane Transport Proteins
Striatonigral Degeneration
SPECT
Esclerose Amiotrófica Lateral
Doença de Parkinson
Proteínas da Membrana Plasmática de Transporte de Dopamina
Degeneração Estriatonigral
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1755282
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Summary:Background The coexistence of amyotrophic lateral sclerosis (ALS) with clinical forms of Parkinson disease (PD), although uncommon, is found to a greater degree than one would expect by chance. The pathological mechanisms of ALS and PD are still not fully understood, and the coexistence of these two diseases suggests that they could share mechanisms in common.
ISSN:0004-282X
1678-4227

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