Analysis of Caspase-9 protein and microRNAs miR-21, miR-126 and miR-155 related to the apoptosis mechanism in the cerebellum of rats submitted to focal cerebral ischemia associated with an alcoholism model

Analysis of Caspase-9 protein and microRNAs miR-21, miR-126 and miR-155 related to the apoptosis mechanism in the cerebellum of rats submitted to focal cerebral ischemia associated with an alcoholism model

ABSTRACT This study aimed to analyze the cerebellum of rats submitted to an experimental focal cerebral ischemia, by middle cerebral artery occlusion for 90 minutes, followed by reperfusion for 48 hours, associated with an alcoholism model. Methods Fifty adult Wistar rats were used, subdivided int...

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Bibliographic Details
Main Authors: Jairo Pinheiro da SILVA, Fermino Sanches LIZARTE NETO, Mucio Luiz de Assis CIRINO, Camila Albuquerque Melo de CARVALHO, Carlos Gilberto CARLOTTI JR, Benedicto Oscar COLLI, Daniela Pretti da Cunha TIRAPELLI, Luís Fernando TIRAPELLI
Format: Article
Language:English
Published: Thieme Revinter Publicações 2019-10-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Brain ischemia
alcoholism
cerebellum
apoptosis
microRNAs
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019001000689&tlng=en
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