Targeting Thyroid Hormone Receptor Interacting Protein (TRIP13) for Cancer Therapy: A Promising Approach

Targeting Thyroid Hormone Receptor Interacting Protein (TRIP13) for Cancer Therapy: A Promising Approach

TRIP13 is a member of the large AAA+ ATPase protein superfamily that plays a crucial role in the precise segregation of chromosomes during mitosis. The abnormal function of TRIP13 has diverse functions, including mitotic processes, DNA repair pathways, and spindle assembly checkpoints, which may con...

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Bibliographic Details
Main Authors: Surya P. Singh, Krishnendu Goswami, Gopal Pathuri, Chinthalapally V. Rao, Venkateshwar Madka
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:DNA
Subjects:
TRIP13
cancer
DNA repair
mitosis
chromosomal instability
drug resistance
Online Access:https://www.mdpi.com/2673-8856/5/1/3
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