Analyzing the ophthalmic red reflex test in children with congenital Zika syndrome
ABSTRACT Objective: To evaluate the red reflex test in children with congenital Zika syndrome in order to predict the occurrence of retinal lesion or optic nerve hypoplasia in these patients. Methods: A descriptive cohort study was conducted in children with Congenital Zika Syndrome. The red refle...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Oftalmologia
2025-06-01
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| Series: | Revista Brasileira de Oftalmologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802025000100218&lng=en&tlng=en |
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| Summary: | ABSTRACT Objective: To evaluate the red reflex test in children with congenital Zika syndrome in order to predict the occurrence of retinal lesion or optic nerve hypoplasia in these patients. Methods: A descriptive cohort study was conducted in children with Congenital Zika Syndrome. The red reflex test was performed with a direct ophthalmoscope, and it was repeated after pupils’ dilation. The patients underwent a comprehensive ophthalmological evaluation. Eye fundus was analyzed by binocular indirect ophthalmoscopy. The occurrence of macular atrophy or optic nerve hypoplasia was recorded. Results: A total of 144 eyes from 72 infants were included. All children had microcephaly. The mean age ranged from 1 to 18 months of life (median = 10 months), and 54.2% were female. Congenital Zika syndrome ocular features (macular atrophy or optic nerve hypoplasia) were detected in a total of 50 eyes. In all of the 144 eyes, the red reflex was present, thus the red reflex test was considered normal without or with pupillary dilation, despite differences in the color nuances observed. Conclusion: Red reflex test did not enhance the assessment of the occurrence of macular atrophic lesion or optic nerve hypoplasia in patients with congenital Zika syndrome. |
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| ISSN: | 1982-8551 |