METTL3-dependent m6A modification of GHR mRNA regulates mitochondrial function through mitochondrial biogenesis during myoblast differentiation

N6-methyl-adenosine (m6A) methylation has recently been shown to play a critical role in muscle development. We recently revealed that local GHR knockdown impairs mitochondrial function by inhibiting mitochondrial biogenesis, thereby repressing myoblast differentiation. And we identified m6A modific...

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Bibliographic Details
Main Authors: Changbin Zhao, Bowen Hu, Zhijun Wang, Ze Zhang, Wen Luo, Hongmei Li, Xiquan Zhang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Poultry Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125004584
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