The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients

Purpose: The purpose of this study is to investigate the impact of smoking on platelet indices among patients with acute myocardial infarction (AMI), and to highlight comparative dimensions between smokers and non-smokers. Materials and Methods: A patient diagnosed with AMI and scheduled for coro...

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Main Authors: Muhammet Salih Ateş, Fikret Keleş, Alp Yıldırım, Zafer Kök, Mustafa Çelik, Bilal İlanbey, Muhammed Fatih Kaleli
Format: Article
Language:English
Published: Kirsehir Ahi Evran University 2024-12-01
Series:Ahi Evran Medical Journal
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Online Access:https://dergipark.org.tr/tr/download/article-file/3793322
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author Muhammet Salih Ateş
Fikret Keleş
Alp Yıldırım
Zafer Kök
Mustafa Çelik
Bilal İlanbey
Muhammed Fatih Kaleli
author_facet Muhammet Salih Ateş
Fikret Keleş
Alp Yıldırım
Zafer Kök
Mustafa Çelik
Bilal İlanbey
Muhammed Fatih Kaleli
author_sort Muhammet Salih Ateş
collection DOAJ
description Purpose: The purpose of this study is to investigate the impact of smoking on platelet indices among patients with acute myocardial infarction (AMI), and to highlight comparative dimensions between smokers and non-smokers. Materials and Methods: A patient diagnosed with AMI and scheduled for coronary angiography between November 2023 and March 2024 was included in this study. Participants were divided into two groups based on their smoking status. Platelet indices, including platelet count, mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT), were compared. Subsequently, the smoking patients were categorized into five groups based on their smoking duration. Results: In the study, which included 224 patients, MPV values in the NSTEMI group among non-smokers were found to be significantly higher compared to the STEMI group (p=0.013). When the relationship between smoking duration and platelet indices was analyzed, it was observed that with increasing smoking duration, platelet indices significantly decreased (p<0.001), platelet count increased (p<0.001), PDW decreased (p=0.02), PCT increased (p=0.001), and MPV decreased (p=0.002). Conclusion: The findings indicate that smoking has significant effects on platelet indices in AMI patients. Particularly, changes in platelet functions associated with increased duration of smoking are of importance for the progression of cardiovascular diseases and the increase in thrombogenic risk. These results highlights the need for a deeper understanding of the effects of smoking on platelet function and the consideration of these effects in the management of cardiovascular risk.
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publishDate 2024-12-01
publisher Kirsehir Ahi Evran University
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series Ahi Evran Medical Journal
spelling doaj-art-95d7f483e0f6456e9cb0d26f6fb5e9232025-08-20T01:47:44ZengKirsehir Ahi Evran UniversityAhi Evran Medical Journal2619-92032024-12-018334234710.46332/aemj.1452480The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction PatientsMuhammet Salih Ateş0https://orcid.org/0000-0003-4099-0064Fikret Keleş1https://orcid.org/0000-0003-1012-3875Alp Yıldırım2https://orcid.org/0000-0002-8517-2033Zafer Kök3https://orcid.org/0000-0001-7458-9135Mustafa Çelik4https://orcid.org/0000-0003-4102-1564Bilal İlanbey5https://orcid.org/0000-0002-7614-281XMuhammed Fatih Kaleli6https://orcid.org/0000-0001-7649-5503AHİ EVRAN ÜNİVERSİTESİKIRŞEHİR AHİ EVRAN ÜNİVERSİTESİ, TIP FAKÜLTESİAHİ EVRAN ÜNİVERSİTESİ, TIP FAKÜLTESİKIRŞEHİR EĞİTİM ARAŞTIRMA HASTANESİ NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ, MERAM TIP PR.AHİ EVRAN ÜNİVERSİTESİ, TIP FAKÜLTESİNECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ, MERAM TIP PR.Purpose: The purpose of this study is to investigate the impact of smoking on platelet indices among patients with acute myocardial infarction (AMI), and to highlight comparative dimensions between smokers and non-smokers. Materials and Methods: A patient diagnosed with AMI and scheduled for coronary angiography between November 2023 and March 2024 was included in this study. Participants were divided into two groups based on their smoking status. Platelet indices, including platelet count, mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT), were compared. Subsequently, the smoking patients were categorized into five groups based on their smoking duration. Results: In the study, which included 224 patients, MPV values in the NSTEMI group among non-smokers were found to be significantly higher compared to the STEMI group (p=0.013). When the relationship between smoking duration and platelet indices was analyzed, it was observed that with increasing smoking duration, platelet indices significantly decreased (p<0.001), platelet count increased (p<0.001), PDW decreased (p=0.02), PCT increased (p=0.001), and MPV decreased (p=0.002). Conclusion: The findings indicate that smoking has significant effects on platelet indices in AMI patients. Particularly, changes in platelet functions associated with increased duration of smoking are of importance for the progression of cardiovascular diseases and the increase in thrombogenic risk. These results highlights the need for a deeper understanding of the effects of smoking on platelet function and the consideration of these effects in the management of cardiovascular risk.https://dergipark.org.tr/tr/download/article-file/3793322acute coronary syndromecardiovascular riskplatelet functiontobacco
spellingShingle Muhammet Salih Ateş
Fikret Keleş
Alp Yıldırım
Zafer Kök
Mustafa Çelik
Bilal İlanbey
Muhammed Fatih Kaleli
The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients
Ahi Evran Medical Journal
acute coronary syndrome
cardiovascular risk
platelet function
tobacco
title The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients
title_full The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients
title_fullStr The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients
title_full_unstemmed The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients
title_short The Impact of Smoking on Platelet Indices Among Acute Myocardial Infarction Patients
title_sort impact of smoking on platelet indices among acute myocardial infarction patients
topic acute coronary syndrome
cardiovascular risk
platelet function
tobacco
url https://dergipark.org.tr/tr/download/article-file/3793322
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