Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog
A 6-year-old male castrated golden retriever was presented for inappetence, lethargy, and progressive obtundation. A chemistry panel showed hypernatremia (>190 mmol/L) and hyperchloremia (157 mmol/L). Brain magnetic resonance imaging (MRI) showed severe congenital hydrocephalus with compressi...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2025.1579965/full |
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| author | Maddisen W. Antes Amelia C. Corona Helena Rylander |
| author_facet | Maddisen W. Antes Amelia C. Corona Helena Rylander |
| author_sort | Maddisen W. Antes |
| collection | DOAJ |
| description | A 6-year-old male castrated golden retriever was presented for inappetence, lethargy, and progressive obtundation. A chemistry panel showed hypernatremia (>190 mmol/L) and hyperchloremia (157 mmol/L). Brain magnetic resonance imaging (MRI) showed severe congenital hydrocephalus with compression of major brain structures, including marked thinning of gray and white matter of the prosencephalon. Results of cerebrospinal fluid (CSF) analysis were within the reference range. A hypodipsic hypernatremia was suspected secondary to dysregulation of the osmoreceptors controlling the thirst center due to progression of hydrocephalus. The dog was treated with intravenous (IV) fluids to slowly reduce the hypernatremia over several days. Mental status improved with normalization of the blood sodium level. Increased stress due to a long car ride and a change in routine may have been the catalyst for the hypodipsia. Hypodipsic hypernatremia is a rare complication of hydrocephalus and should be on the differential list when a sudden change in mentation occurs in dogs with hydrocephalus. |
| format | Article |
| id | doaj-art-95d71646344b48ff8288fab8d8b863dc |
| institution | Kabale University |
| issn | 2297-1769 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj-art-95d71646344b48ff8288fab8d8b863dc2025-08-20T03:49:46ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692025-05-011210.3389/fvets.2025.15799651579965Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dogMaddisen W. AntesAmelia C. CoronaHelena RylanderA 6-year-old male castrated golden retriever was presented for inappetence, lethargy, and progressive obtundation. A chemistry panel showed hypernatremia (>190 mmol/L) and hyperchloremia (157 mmol/L). Brain magnetic resonance imaging (MRI) showed severe congenital hydrocephalus with compression of major brain structures, including marked thinning of gray and white matter of the prosencephalon. Results of cerebrospinal fluid (CSF) analysis were within the reference range. A hypodipsic hypernatremia was suspected secondary to dysregulation of the osmoreceptors controlling the thirst center due to progression of hydrocephalus. The dog was treated with intravenous (IV) fluids to slowly reduce the hypernatremia over several days. Mental status improved with normalization of the blood sodium level. Increased stress due to a long car ride and a change in routine may have been the catalyst for the hypodipsia. Hypodipsic hypernatremia is a rare complication of hydrocephalus and should be on the differential list when a sudden change in mentation occurs in dogs with hydrocephalus.https://www.frontiersin.org/articles/10.3389/fvets.2025.1579965/fullhypernatremiahypodipsiahydrocephalusmentationdog |
| spellingShingle | Maddisen W. Antes Amelia C. Corona Helena Rylander Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog Frontiers in Veterinary Science hypernatremia hypodipsia hydrocephalus mentation dog |
| title | Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog |
| title_full | Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog |
| title_fullStr | Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog |
| title_full_unstemmed | Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog |
| title_short | Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog |
| title_sort | case report hypodipsic hypernatremia secondary to hydrocephalus in a dog |
| topic | hypernatremia hypodipsia hydrocephalus mentation dog |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2025.1579965/full |
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