ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE
Not only thrombotic, but also “non-thrombotic” mechanisms of antiphospholipid antibodies are being actively studied in regard to their impact on the structure of reproductive losses and other complications of pregnancy. Non-thrombotic effects of APA include the damage of cells, the induction of apop...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-06-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/65 |
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| author | V. O. Bitsadze D. Kh. Khizroeva N. A. Makatsariya E. S. Egorova S. M. Baymuradova T. Ya. Mashkova |
| author_facet | V. O. Bitsadze D. Kh. Khizroeva N. A. Makatsariya E. S. Egorova S. M. Baymuradova T. Ya. Mashkova |
| author_sort | V. O. Bitsadze |
| collection | DOAJ |
| description | Not only thrombotic, but also “non-thrombotic” mechanisms of antiphospholipid antibodies are being actively studied in regard to their impact on the structure of reproductive losses and other complications of pregnancy. Non-thrombotic effects of APA include the damage of cells, the induction of apoptosis, the inhibition of proliferation, the suppression of human chorionic gonadotropin, the interference to the invasion of the trophoblast, and defectsof differentiation of the endometrium. Thrombotic effects are: widespread thrombosis, placental infarction, disruption of the annexin barrier, and anti-b2GPI and APC resistance. |
| format | Article |
| id | doaj-art-95d5a2ebc11e4f9a8a524aeed8c95860 |
| institution | Kabale University |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2016-06-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-95d5a2ebc11e4f9a8a524aeed8c958602025-08-20T03:39:40ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-0182396063ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICEV. O. Bitsadze0D. Kh. Khizroeva1N. A. Makatsariya2E. S. Egorova3S. M. Baymuradova4T. Ya. Mashkova5First Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationNot only thrombotic, but also “non-thrombotic” mechanisms of antiphospholipid antibodies are being actively studied in regard to their impact on the structure of reproductive losses and other complications of pregnancy. Non-thrombotic effects of APA include the damage of cells, the induction of apoptosis, the inhibition of proliferation, the suppression of human chorionic gonadotropin, the interference to the invasion of the trophoblast, and defectsof differentiation of the endometrium. Thrombotic effects are: widespread thrombosis, placental infarction, disruption of the annexin barrier, and anti-b2GPI and APC resistance.https://www.gynecology.su/jour/article/view/65antiphospholipid antibodiesantiphospholipid syndromecomplications of pregnancycatastrophis antiphospholipid syndrome |
| spellingShingle | V. O. Bitsadze D. Kh. Khizroeva N. A. Makatsariya E. S. Egorova S. M. Baymuradova T. Ya. Mashkova ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE Акушерство, гинекология и репродукция antiphospholipid antibodies antiphospholipid syndrome complications of pregnancy catastrophis antiphospholipid syndrome |
| title | ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE |
| title_full | ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE |
| title_fullStr | ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE |
| title_full_unstemmed | ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE |
| title_short | ANTIPHOSPHOLIPID ANTIBODIES, THEIR PATHOGENETIC AND DIAGNOSTIC ISSUES OBSTETRIC PRACTICE |
| title_sort | antiphospholipid antibodies their pathogenetic and diagnostic issues obstetric practice |
| topic | antiphospholipid antibodies antiphospholipid syndrome complications of pregnancy catastrophis antiphospholipid syndrome |
| url | https://www.gynecology.su/jour/article/view/65 |
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