Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis
Purpose: To evaluate the Visual and Refractive outcomes of Photorefractive Keratectomy(PRK) in Patients with Hyperopia and Hyperopic-astigmatismMethods: This meta-analysis followed the PRISMA statement. Literature search of databases including PubMed, web of science, Scopus, Medline, Cochrane librar...
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Elsevier
2025-06-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100025001322 |
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| author | Samira Hassanzadeh Firouzeh Fereydouni Elham Bakhtiari |
| author_facet | Samira Hassanzadeh Firouzeh Fereydouni Elham Bakhtiari |
| author_sort | Samira Hassanzadeh |
| collection | DOAJ |
| description | Purpose: To evaluate the Visual and Refractive outcomes of Photorefractive Keratectomy(PRK) in Patients with Hyperopia and Hyperopic-astigmatismMethods: This meta-analysis followed the PRISMA statement. Literature search of databases including PubMed, web of science, Scopus, Medline, Cochrane library and Google-Scholar was done to find relevant published articles about outcomes of PRK surgery for hyperopic and compound hyperopic-astigmatism. The search was conducted with no time or language restriction; and was updated until 31th December 2023. Open Meta Analyst software was used for data analysis. The combined effect of continuous data was presented by mean difference and 95 % confidence interval (CI).Results: A total of 750 eyes from 481 patients (49.5 % female and 50.5 % male) were analyzed. The postoperative improvement in UCVA(uncorrected visual acuity), SE(spherical equivalent) and cylindrical power in these samples were statistically significant(P = 0.001). The overall incidence of corneal haze was 32.5 %(95 % CI:[26.5 %, 38.4 %]).Conclusions: The Visual and Refractive outcomes of PRK in Patients with Hyperopia and Hyperopic-astigmatism are satisfactory, but its 32.5 % haze incidence is significantly higher than in myopic PRK and Trans-PRK(trans-epithelial PRK), raising safety concerns. Further research is needed to reduce haze and enhance outcomes. |
| format | Article |
| id | doaj-art-95d48a24802b4bc48df1fb2c7dc3c265 |
| institution | DOAJ |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
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| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-95d48a24802b4bc48df1fb2c7dc3c2652025-08-20T02:57:46ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-06-015310460410.1016/j.pdpdt.2025.104604Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysisSamira Hassanzadeh0Firouzeh Fereydouni1Elham Bakhtiari2Department of Optometry, School of Paramedical and Rehabilitation Sciences, Mashhad University Of Medical Science, Mashhad, , IranDepartment of Optometry, School of Paramedical and Rehabilitation Sciences, Mashhad University Of Medical Science, Mashhad, , Iran; Corresponding author: in Optometry, Department of Optometry, School of Paramedical and Rehabilitation Sciences, Mashhad University Of Medical Science, Mashhad, Iran.Eye Research Center, Mashhad University of Medical Sciences, Mashhad, IranPurpose: To evaluate the Visual and Refractive outcomes of Photorefractive Keratectomy(PRK) in Patients with Hyperopia and Hyperopic-astigmatismMethods: This meta-analysis followed the PRISMA statement. Literature search of databases including PubMed, web of science, Scopus, Medline, Cochrane library and Google-Scholar was done to find relevant published articles about outcomes of PRK surgery for hyperopic and compound hyperopic-astigmatism. The search was conducted with no time or language restriction; and was updated until 31th December 2023. Open Meta Analyst software was used for data analysis. The combined effect of continuous data was presented by mean difference and 95 % confidence interval (CI).Results: A total of 750 eyes from 481 patients (49.5 % female and 50.5 % male) were analyzed. The postoperative improvement in UCVA(uncorrected visual acuity), SE(spherical equivalent) and cylindrical power in these samples were statistically significant(P = 0.001). The overall incidence of corneal haze was 32.5 %(95 % CI:[26.5 %, 38.4 %]).Conclusions: The Visual and Refractive outcomes of PRK in Patients with Hyperopia and Hyperopic-astigmatism are satisfactory, but its 32.5 % haze incidence is significantly higher than in myopic PRK and Trans-PRK(trans-epithelial PRK), raising safety concerns. Further research is needed to reduce haze and enhance outcomes.http://www.sciencedirect.com/science/article/pii/S1572100025001322PRKPhotoreractivekeratectomyHyperopiaHyperopic-astigmatismRefractive errorRefractive surgery |
| spellingShingle | Samira Hassanzadeh Firouzeh Fereydouni Elham Bakhtiari Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis Photodiagnosis and Photodynamic Therapy PRK Photoreractivekeratectomy Hyperopia Hyperopic-astigmatism Refractive error Refractive surgery |
| title | Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis |
| title_full | Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis |
| title_fullStr | Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis |
| title_full_unstemmed | Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis |
| title_short | Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis |
| title_sort | visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic astigmatism a systematic review and meta analysis |
| topic | PRK Photoreractivekeratectomy Hyperopia Hyperopic-astigmatism Refractive error Refractive surgery |
| url | http://www.sciencedirect.com/science/article/pii/S1572100025001322 |
| work_keys_str_mv | AT samirahassanzadeh visualandrefractiveoutcomesofphotorefractivekeratectomyinhyperopiaandhyperopicastigmatismasystematicreviewandmetaanalysis AT firouzehfereydouni visualandrefractiveoutcomesofphotorefractivekeratectomyinhyperopiaandhyperopicastigmatismasystematicreviewandmetaanalysis AT elhambakhtiari visualandrefractiveoutcomesofphotorefractivekeratectomyinhyperopiaandhyperopicastigmatismasystematicreviewandmetaanalysis |