THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERS
Aim. To establish insecticide surface skin exposure standards and predict the risk of occupational skin pathology in agricultural workers to develop preventive measures against diseases caused by dermal pesticide exposure. Materials and methods. A field experiment was conducted in accordance with...
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| Format: | Article |
| Language: | English |
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State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department
2025-04-01
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| Series: | Клінічна та профілактична медицина |
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| Online Access: | https://cp-medical.com/index.php/journal/article/view/585 |
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| author | Heorhii P. Bardov Mykola V. Kondratiuk Olena P. Vavrinevych Oleksandr S. Vavrinevych |
| author_facet | Heorhii P. Bardov Mykola V. Kondratiuk Olena P. Vavrinevych Oleksandr S. Vavrinevych |
| author_sort | Heorhii P. Bardov |
| collection | DOAJ |
| description | Aim. To establish insecticide surface skin exposure standards and predict the risk of occupational skin pathology in agricultural workers to develop preventive measures against diseases caused by dermal pesticide exposure.
Materials and methods. A field experiment was conducted in accordance with the latest requirements of the European Food Safety Authority (2022), and risk assessment was performed following the Recommendations approved by the Ministry of Health of Ukraine (Order No. 324 dated 13.05.2009) under different pesticide application methods: boom, fan airblast, pre-planting, aerial, and knapsack spraying. A total of 27 field experiment series were conducted, and air samples from the working area (n=68) as well as dermal exposure levels (n=68) were analyzed for each worker engaged in various pesticide application methods. The quantitative determination of pesticide content was carried out using gas-liquid chromatography and high-performance liquid chromatography. Statistical analysis of the results was performed using the licensed statistical software packages MedStat v.5.2 (Copyright © 2003-2019) and Python 3.11; for data storage – Microsoft® Excel® for Microsoft 365 MSO.
Results. The presence of insecticide contamination was predominantly detected on gloves worn by operators during the preparation of working solutions. No direct contamination of the skin surface was identified, with only residual traces found on workers' protective clothing. A comparison of the exposure dose from percutaneous absorption during technological operations under different application methods, the acceptable dermal exposure level of insecticides for workers (DE AOEL), the allowable percutaneous dose for occupational groups (ADderm), and hazard coefficients for percutaneous absorption (HCderm) revealed significant differences in dermal exposure between different application methods, whereas no significant differences were observed within the same method.
Conclusions. When comparing hazard coefficients for percutaneous absorption calculated using different models, no significant differences were found between the risks assessed using DE AOEL and ADderm for individual technological operations across different application methods, except for knapsack spraying operators. The risk calculated using ADderm was significantly lower compared to the risk estimated with DE AOEL. |
| format | Article |
| id | doaj-art-95d20a42199249a5ae570cccf7266264 |
| institution | Kabale University |
| issn | 2616-4868 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department |
| record_format | Article |
| series | Клінічна та профілактична медицина |
| spelling | doaj-art-95d20a42199249a5ae570cccf72662642025-08-20T03:50:31ZengState Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative DepartmentКлінічна та профілактична медицина2616-48682025-04-01411612610.31612/2616-4868.4.2025.15585THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERSHeorhii P. Bardov0Mykola V. Kondratiuk1Olena P. Vavrinevych2Oleksandr S. Vavrinevych3Bogomolets National Medical University, Kyiv, UkraineBogomolets National Medical University, Kyiv, UkraineBogomolets National Medical University, Kyiv, UkraineBogomolets National Medical University, Kyiv, UkraineAim. To establish insecticide surface skin exposure standards and predict the risk of occupational skin pathology in agricultural workers to develop preventive measures against diseases caused by dermal pesticide exposure. Materials and methods. A field experiment was conducted in accordance with the latest requirements of the European Food Safety Authority (2022), and risk assessment was performed following the Recommendations approved by the Ministry of Health of Ukraine (Order No. 324 dated 13.05.2009) under different pesticide application methods: boom, fan airblast, pre-planting, aerial, and knapsack spraying. A total of 27 field experiment series were conducted, and air samples from the working area (n=68) as well as dermal exposure levels (n=68) were analyzed for each worker engaged in various pesticide application methods. The quantitative determination of pesticide content was carried out using gas-liquid chromatography and high-performance liquid chromatography. Statistical analysis of the results was performed using the licensed statistical software packages MedStat v.5.2 (Copyright © 2003-2019) and Python 3.11; for data storage – Microsoft® Excel® for Microsoft 365 MSO. Results. The presence of insecticide contamination was predominantly detected on gloves worn by operators during the preparation of working solutions. No direct contamination of the skin surface was identified, with only residual traces found on workers' protective clothing. A comparison of the exposure dose from percutaneous absorption during technological operations under different application methods, the acceptable dermal exposure level of insecticides for workers (DE AOEL), the allowable percutaneous dose for occupational groups (ADderm), and hazard coefficients for percutaneous absorption (HCderm) revealed significant differences in dermal exposure between different application methods, whereas no significant differences were observed within the same method. Conclusions. When comparing hazard coefficients for percutaneous absorption calculated using different models, no significant differences were found between the risks assessed using DE AOEL and ADderm for individual technological operations across different application methods, except for knapsack spraying operators. The risk calculated using ADderm was significantly lower compared to the risk estimated with DE AOEL.https://cp-medical.com/index.php/journal/article/view/585acceptable operator exposure levelpotential skin exposurepesticidesrisk assessmentoccupational exposurepersonal protective equipment |
| spellingShingle | Heorhii P. Bardov Mykola V. Kondratiuk Olena P. Vavrinevych Oleksandr S. Vavrinevych THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERS Клінічна та профілактична медицина acceptable operator exposure level potential skin exposure pesticides risk assessment occupational exposure personal protective equipment |
| title | THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERS |
| title_full | THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERS |
| title_fullStr | THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERS |
| title_full_unstemmed | THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERS |
| title_short | THE ISSUE OF INSECTICIDE REGULATION ON SKIN SURFACE FOR PREDICTING THE RISK OF OCCUPATIONAL SKIN PATHOLOGY IN AGRICULTURAL WORKERS |
| title_sort | issue of insecticide regulation on skin surface for predicting the risk of occupational skin pathology in agricultural workers |
| topic | acceptable operator exposure level potential skin exposure pesticides risk assessment occupational exposure personal protective equipment |
| url | https://cp-medical.com/index.php/journal/article/view/585 |
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