In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar Survival

BACKGROUND: Sorafenib, an oral multityrosine kinase inhibitor, has been approved for treatment of unresectable hepatocellular carcinoma (HCC). British Columbia (BC) was the first province in Canada to provide drug coverage for sorafenib.

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Main Authors: Alexandra Shingina, Al Moutaz Hashim, Mazhar Haque, Michael Suen, Eric M Yoshida, Sharlene Gill, Fergal Donnellan, Alan A Weiss
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2013/170546
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author Alexandra Shingina
Al Moutaz Hashim
Mazhar Haque
Michael Suen
Eric M Yoshida
Sharlene Gill
Fergal Donnellan
Alan A Weiss
author_facet Alexandra Shingina
Al Moutaz Hashim
Mazhar Haque
Michael Suen
Eric M Yoshida
Sharlene Gill
Fergal Donnellan
Alan A Weiss
author_sort Alexandra Shingina
collection DOAJ
description BACKGROUND: Sorafenib, an oral multityrosine kinase inhibitor, has been approved for treatment of unresectable hepatocellular carcinoma (HCC). British Columbia (BC) was the first province in Canada to provide drug coverage for sorafenib.
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language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology
spelling doaj-art-95cebbf611d04a0a8cdf5e2a83ce333b2025-08-20T02:10:06ZengWileyCanadian Journal of Gastroenterology0835-79002013-01-0127739339610.1155/2013/170546In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar SurvivalAlexandra Shingina0Al Moutaz Hashim1Mazhar Haque2Michael Suen3Eric M Yoshida4Sharlene Gill5Fergal Donnellan6Alan A Weiss7Department of Medicine, Division of Gastroenterology, Department of Obstetrics and Gynecology, University of British Columbia, CanadaDepartment of Medicine, Division of Gastroenterology, Department of Obstetrics and Gynecology, University of British Columbia, CanadaDepartment of Medicine, Division of Gastroenterology, Department of Obstetrics and Gynecology, University of British Columbia, CanadaDepartment of Medical Oncology, The British Columbia Cancer Agency, Vancouver, British Columbia, CanadaDepartment of Medicine, Division of Gastroenterology, Department of Obstetrics and Gynecology, University of British Columbia, CanadaDepartment of Medical Oncology, The British Columbia Cancer Agency, Vancouver, British Columbia, CanadaDepartment of Medicine, Division of Gastroenterology, Department of Obstetrics and Gynecology, University of British Columbia, CanadaDepartment of Medicine, Division of Gastroenterology, Department of Obstetrics and Gynecology, University of British Columbia, CanadaBACKGROUND: Sorafenib, an oral multityrosine kinase inhibitor, has been approved for treatment of unresectable hepatocellular carcinoma (HCC). British Columbia (BC) was the first province in Canada to provide drug coverage for sorafenib.http://dx.doi.org/10.1155/2013/170546
spellingShingle Alexandra Shingina
Al Moutaz Hashim
Mazhar Haque
Michael Suen
Eric M Yoshida
Sharlene Gill
Fergal Donnellan
Alan A Weiss
In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar Survival
Canadian Journal of Gastroenterology
title In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar Survival
title_full In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar Survival
title_fullStr In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar Survival
title_full_unstemmed In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar Survival
title_short In a ‘Real-World’, Clinic-Based Community Setting, Sorafenib Dose of 400 mg/day is as Effective as Standard Dose of 800 mg/day in Patients with Advanced Hepatocellular Carcimona, with Better Tolerance and Similar Survival
title_sort in a real world clinic based community setting sorafenib dose of 400 mg day is as effective as standard dose of 800 mg day in patients with advanced hepatocellular carcimona with better tolerance and similar survival
url http://dx.doi.org/10.1155/2013/170546
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