A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus
Morphea is an uncommon connective tissue disease with the most prominent feature being thickening or fibrosis of the dermal without internal organ involvement. It is also known as a part of localized scleroderma. Based on clinical presentation and depth of tissue involvement, morphea is classified...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2015-04-01
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| Series: | Acta Medica Indonesiana |
| Online Access: | https://mail.actamedindones.org/index.php/ijim/article/view/50 |
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| author | Wardhana Wardhana EA Datau |
| author_facet | Wardhana Wardhana EA Datau |
| author_sort | Wardhana Wardhana |
| collection | DOAJ |
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Morphea is an uncommon connective tissue disease with the most prominent feature being thickening or fibrosis of the dermal without internal organ involvement. It is also known as a part of localized scleroderma. Based on clinical presentation and depth of tissue involvement, morphea is classified into several forms, and about two thirds of adults with morphea have plaque type. Overproduction of collagen production by fibroblast is the cause of abnormality in morphea, and the hyperactivity mechanism of fibroblast is still unknown, although there are several mechanisms already proposed. Plaque type morphea is actually a benign and self limited. Plaque type morphea that mimicking systemic lupus erythematosus in clinical appearance, such as alopecia and oral mucosal ulcers, is uncommon.
A case of plaque type morphea mimicking systemic lupus erythematosus in a 20 year old woman was discussed. The patient was treated with local and systemic immunosuppressant and antioxydant. The patient’s condition is improved without any significant side effects.
Key words: morphea, plaque type.
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| format | Article |
| id | doaj-art-95c1ff0aa1e244f2948a03b70759d31f |
| institution | Kabale University |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2015-04-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-95c1ff0aa1e244f2948a03b70759d31f2025-08-20T03:36:18ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322015-04-01472A Patient With Plaque Type Morphea Mimicking Systemic Lupus ErythematosusWardhana Wardhana0EA Datau1Department of Internal Medicine, Siloam International Hospitals. Karawaci, IndonesiaDepartment of Internal Medicine, Prof. Dr. RD Kandou General Hospital & Sitti Maryam Islamic Hospital, Manado, North Sulawesi, Indonesia Morphea is an uncommon connective tissue disease with the most prominent feature being thickening or fibrosis of the dermal without internal organ involvement. It is also known as a part of localized scleroderma. Based on clinical presentation and depth of tissue involvement, morphea is classified into several forms, and about two thirds of adults with morphea have plaque type. Overproduction of collagen production by fibroblast is the cause of abnormality in morphea, and the hyperactivity mechanism of fibroblast is still unknown, although there are several mechanisms already proposed. Plaque type morphea is actually a benign and self limited. Plaque type morphea that mimicking systemic lupus erythematosus in clinical appearance, such as alopecia and oral mucosal ulcers, is uncommon. A case of plaque type morphea mimicking systemic lupus erythematosus in a 20 year old woman was discussed. The patient was treated with local and systemic immunosuppressant and antioxydant. The patient’s condition is improved without any significant side effects. Key words: morphea, plaque type. https://mail.actamedindones.org/index.php/ijim/article/view/50 |
| spellingShingle | Wardhana Wardhana EA Datau A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus Acta Medica Indonesiana |
| title | A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus |
| title_full | A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus |
| title_fullStr | A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus |
| title_full_unstemmed | A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus |
| title_short | A Patient With Plaque Type Morphea Mimicking Systemic Lupus Erythematosus |
| title_sort | patient with plaque type morphea mimicking systemic lupus erythematosus |
| url | https://mail.actamedindones.org/index.php/ijim/article/view/50 |
| work_keys_str_mv | AT wardhanawardhana apatientwithplaquetypemorpheamimickingsystemiclupuserythematosus AT eadatau apatientwithplaquetypemorpheamimickingsystemiclupuserythematosus AT wardhanawardhana patientwithplaquetypemorpheamimickingsystemiclupuserythematosus AT eadatau patientwithplaquetypemorpheamimickingsystemiclupuserythematosus |