Slowly progressive aphasia followed by Alzheimer' s dementia: a case report

Slowly progressive aphasia has been found in 8 published cases, 2 of whom progressed over a period of years to generalized dementia. Positron emission tomography demonstrated decreased glucose metabolism in the left perisylvian region in 2 cases. We describe a patient who had slowly progressive apha...

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Main Authors: Silmara A. V. de Oliveira, Maria Júlia M. de O. Castro, Paulo Rogério M. Bittencourt
Format: Article
Language:English
Published: Thieme Revinter Publicações 1989-03-01
Series:Arquivos de Neuro-Psiquiatria
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1989000100009&lng=en&tlng=en
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author Silmara A. V. de Oliveira
Maria Júlia M. de O. Castro
Paulo Rogério M. Bittencourt
author_facet Silmara A. V. de Oliveira
Maria Júlia M. de O. Castro
Paulo Rogério M. Bittencourt
author_sort Silmara A. V. de Oliveira
collection DOAJ
description Slowly progressive aphasia has been found in 8 published cases, 2 of whom progressed over a period of years to generalized dementia. Positron emission tomography demonstrated decreased glucose metabolism in the left perisylvian region in 2 cases. We describe a patient who had slowly progressive aphasia and developed generalized Alzheimer's dementia 7 years after presentation. There was no clinical or laboratory evidence of concomitant disease. Computerized tomography showed generalized atrophy more marked on the left perisylvian region late in the disease, when EEG showed generalized slowing more marked on the same area. Slowly progressive aphasia of old age should be considered a separate entity until further studies elucidate its relation to Alzheimer's dementia.
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institution OA Journals
issn 1678-4227
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publisher Thieme Revinter Publicações
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-95c19745c859413795d8e8bbc23241ae2025-08-20T01:58:28ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271989-03-01471727510.1590/S0004-282X1989000100009S0004-282X1989000100009Slowly progressive aphasia followed by Alzheimer' s dementia: a case reportSilmara A. V. de Oliveira0Maria Júlia M. de O. CastroPaulo Rogério M. BittencourtHospital Nossa Senhora das GraçasSlowly progressive aphasia has been found in 8 published cases, 2 of whom progressed over a period of years to generalized dementia. Positron emission tomography demonstrated decreased glucose metabolism in the left perisylvian region in 2 cases. We describe a patient who had slowly progressive aphasia and developed generalized Alzheimer's dementia 7 years after presentation. There was no clinical or laboratory evidence of concomitant disease. Computerized tomography showed generalized atrophy more marked on the left perisylvian region late in the disease, when EEG showed generalized slowing more marked on the same area. Slowly progressive aphasia of old age should be considered a separate entity until further studies elucidate its relation to Alzheimer's dementia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1989000100009&lng=en&tlng=en
spellingShingle Silmara A. V. de Oliveira
Maria Júlia M. de O. Castro
Paulo Rogério M. Bittencourt
Slowly progressive aphasia followed by Alzheimer' s dementia: a case report
Arquivos de Neuro-Psiquiatria
title Slowly progressive aphasia followed by Alzheimer' s dementia: a case report
title_full Slowly progressive aphasia followed by Alzheimer' s dementia: a case report
title_fullStr Slowly progressive aphasia followed by Alzheimer' s dementia: a case report
title_full_unstemmed Slowly progressive aphasia followed by Alzheimer' s dementia: a case report
title_short Slowly progressive aphasia followed by Alzheimer' s dementia: a case report
title_sort slowly progressive aphasia followed by alzheimer s dementia a case report
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1989000100009&lng=en&tlng=en
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