Adult Neuroplasticity: More Than 40 Years of Research

Within the last four decades, our view of the mature vertebrate brain has changed significantly. Today it is generally accepted that the adult brain is far from being fixed. A number of factors such as stress, adrenal and gonadal hormones, neurotransmitters, growth factors, certain drugs, environmen...

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Main Authors: Eberhard Fuchs, Gabriele Flügge
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2014/541870
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author Eberhard Fuchs
Gabriele Flügge
author_facet Eberhard Fuchs
Gabriele Flügge
author_sort Eberhard Fuchs
collection DOAJ
description Within the last four decades, our view of the mature vertebrate brain has changed significantly. Today it is generally accepted that the adult brain is far from being fixed. A number of factors such as stress, adrenal and gonadal hormones, neurotransmitters, growth factors, certain drugs, environmental stimulation, learning, and aging change neuronal structures and functions. The processes that these factors may induce are morphological alterations in brain areas, changes in neuron morphology, network alterations including changes in neuronal connectivity, the generation of new neurons (neurogenesis), and neurobiochemical changes. Here we review several aspects of neuroplasticity and discuss the functional implications of the neuroplastic capacities of the adult and differentiated brain with reference to the history of their discovery.
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spelling doaj-art-95bd3183d67e4f05a83dba0acdc061272025-08-20T03:20:34ZengWileyNeural Plasticity2090-59041687-54432014-01-01201410.1155/2014/541870541870Adult Neuroplasticity: More Than 40 Years of ResearchEberhard Fuchs0Gabriele Flügge1German Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, 37077 Göttingen, GermanyGerman Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, 37077 Göttingen, GermanyWithin the last four decades, our view of the mature vertebrate brain has changed significantly. Today it is generally accepted that the adult brain is far from being fixed. A number of factors such as stress, adrenal and gonadal hormones, neurotransmitters, growth factors, certain drugs, environmental stimulation, learning, and aging change neuronal structures and functions. The processes that these factors may induce are morphological alterations in brain areas, changes in neuron morphology, network alterations including changes in neuronal connectivity, the generation of new neurons (neurogenesis), and neurobiochemical changes. Here we review several aspects of neuroplasticity and discuss the functional implications of the neuroplastic capacities of the adult and differentiated brain with reference to the history of their discovery.http://dx.doi.org/10.1155/2014/541870
spellingShingle Eberhard Fuchs
Gabriele Flügge
Adult Neuroplasticity: More Than 40 Years of Research
Neural Plasticity
title Adult Neuroplasticity: More Than 40 Years of Research
title_full Adult Neuroplasticity: More Than 40 Years of Research
title_fullStr Adult Neuroplasticity: More Than 40 Years of Research
title_full_unstemmed Adult Neuroplasticity: More Than 40 Years of Research
title_short Adult Neuroplasticity: More Than 40 Years of Research
title_sort adult neuroplasticity more than 40 years of research
url http://dx.doi.org/10.1155/2014/541870
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AT gabrieleflugge adultneuroplasticitymorethan40yearsofresearch