QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case Report

We present the case of a 49-year-old male patient with prosthetic mitral valve endocarditis associated with QT prolongation and torsades de pointes. He was asymptomatic until the end of January 2012, when he was admitted to our hospital emergency unit because of syncope, fever, and suspicion of endo...

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Main Authors: A. Tounsi, L. Abid, M. Akrout, M. Hentati, S. Kammoun
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/574923
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author A. Tounsi
L. Abid
M. Akrout
M. Hentati
S. Kammoun
author_facet A. Tounsi
L. Abid
M. Akrout
M. Hentati
S. Kammoun
author_sort A. Tounsi
collection DOAJ
description We present the case of a 49-year-old male patient with prosthetic mitral valve endocarditis associated with QT prolongation and torsades de pointes. He was asymptomatic until the end of January 2012, when he was admitted to our hospital emergency unit because of syncope, fever, and suspicion of endocarditis. Cardiologic evaluation was requested and the transthoracic (TTE) and transesophageal (TEE) echocardiograms revealed vegetations on the prosthetic mitral valve. All cultures were positive for methicillin-sensitive Staphylococcus aureus. The corrected QT (QTc) interval was markedly prolonged upon admission (QTc 540 ms). He experienced torsades de pointes (TdP) several times and he was recovered after bystander cardiopulmonary resuscitation. The clinical course and the long QTc interval with deep inverted T wave were completely normalized 4 weeks after. He continued on triple antibiotic therapy for 45 days with a good revolution. The clinical features and the possible mechanisms of QT prolongation (inflammation, infection) of this patient are discussed.
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spelling doaj-art-95b319efa9e34f9dbae09d92da8be7c52025-08-20T02:10:06ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/574923574923QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case ReportA. Tounsi0L. Abid1M. Akrout2M. Hentati3S. Kammoun4Cardiology Department, Hedi Chaker University Hospital, Sfax 3029, TunisiaCardiology Department, Hedi Chaker University Hospital, Sfax 3029, TunisiaCardiology Department, Hedi Chaker University Hospital, Sfax 3029, TunisiaCardiology Department, Hedi Chaker University Hospital, Sfax 3029, TunisiaCardiology Department, Hedi Chaker University Hospital, Sfax 3029, TunisiaWe present the case of a 49-year-old male patient with prosthetic mitral valve endocarditis associated with QT prolongation and torsades de pointes. He was asymptomatic until the end of January 2012, when he was admitted to our hospital emergency unit because of syncope, fever, and suspicion of endocarditis. Cardiologic evaluation was requested and the transthoracic (TTE) and transesophageal (TEE) echocardiograms revealed vegetations on the prosthetic mitral valve. All cultures were positive for methicillin-sensitive Staphylococcus aureus. The corrected QT (QTc) interval was markedly prolonged upon admission (QTc 540 ms). He experienced torsades de pointes (TdP) several times and he was recovered after bystander cardiopulmonary resuscitation. The clinical course and the long QTc interval with deep inverted T wave were completely normalized 4 weeks after. He continued on triple antibiotic therapy for 45 days with a good revolution. The clinical features and the possible mechanisms of QT prolongation (inflammation, infection) of this patient are discussed.http://dx.doi.org/10.1155/2012/574923
spellingShingle A. Tounsi
L. Abid
M. Akrout
M. Hentati
S. Kammoun
QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case Report
Case Reports in Medicine
title QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case Report
title_full QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case Report
title_fullStr QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case Report
title_full_unstemmed QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case Report
title_short QT Prolongation Complicated with Torsades de Pointes in Prosthetic Mitral Valve Endocarditis: A Case Report
title_sort qt prolongation complicated with torsades de pointes in prosthetic mitral valve endocarditis a case report
url http://dx.doi.org/10.1155/2012/574923
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