Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study
Aim The REGENERAR registry study aimed to assess the prevalence of pain among Diabetic Peripheral Neuropathy (DPN) patients and to evaluate their health literacy and quality of life.Methods REGENERAR was a prospective, multicentric registry study conducted in primary healthcare units across Portugal...
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Taylor & Francis Group
2025-12-01
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| Series: | Future Science OA |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20565623.2025.2527503 |
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| author | Filipe Antunes Emanuel Airosa Samara Rubio Rodriguez Igor Faria Diogo Anes Teresa Cruz José Miguel Oliveira João Simões Lisandra Dias Carina Faria Pedro Xavier Patrícia Alves Jacinta Pereira Inês Lima Raul Marques Pereira |
| author_facet | Filipe Antunes Emanuel Airosa Samara Rubio Rodriguez Igor Faria Diogo Anes Teresa Cruz José Miguel Oliveira João Simões Lisandra Dias Carina Faria Pedro Xavier Patrícia Alves Jacinta Pereira Inês Lima Raul Marques Pereira |
| author_sort | Filipe Antunes |
| collection | DOAJ |
| description | Aim The REGENERAR registry study aimed to assess the prevalence of pain among Diabetic Peripheral Neuropathy (DPN) patients and to evaluate their health literacy and quality of life.Methods REGENERAR was a prospective, multicentric registry study conducted in primary healthcare units across Portugal. Adults with DPN were enrolled between April and September 2023. Sociodemographic and clinical information, including pain, neuropathic pain, literacy and quality of life were collected at inclusion visit (V1) and end-of-study visit (V2).Results The study enrolled 127 patients, 120 of whom completed V2. At V1, 77.5% of participants reported pain (61.7% at V2, p < 0.001), with neuropathic pain prevalence, assessed by clinical findings and result of DN4 questionnaire, being 48.3% at V1 and 46.7% at V2. Patient literacy on pain as a diabetes mellitus symptom improved from V1 to V2. Quality of life remained stable but suboptimal, with a median score of 70/100 on the EQ-5D-5L scale.Conclusion The REGENERAR registry highlights a high prevalence of pain among DPN patients in Portugal, exceeding international figures, but consistent with literature concerning neuropathic pain. It also identifies critical gaps in both patient and healthcare provider literacy. Addressing these gaps could improve disease management and quality of life. |
| format | Article |
| id | doaj-art-95b17a41cd2846d1ba6a8db8cc291eba |
| institution | Kabale University |
| issn | 2056-5623 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj-art-95b17a41cd2846d1ba6a8db8cc291eba2025-08-20T03:40:41ZengTaylor & Francis GroupFuture Science OA2056-56232025-12-0111110.1080/20565623.2025.2527503Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry studyFilipe Antunes0Emanuel Airosa1Samara Rubio Rodriguez2Igor Faria3Diogo Anes4Teresa Cruz5José Miguel Oliveira6João Simões7Lisandra Dias8Carina Faria9Pedro Xavier10Patrícia Alves11Jacinta Pereira12Inês Lima13Raul Marques Pereira14Physical and Rehabilitation Medicine Department and Chronic Pain Functional Unit, Braga Hospital, Braga, PortugalUnidade de Saúde Familiar Terra da Nóbrega, Vila Verde, PortugalUnidade de Cuidados de Saúde Personalizados Odemira, Odemira, PortugalUnidade de Saúde Familiar Gil Eanes, Viana do Castelo, PortugalUnidade de Cuidados de Saúde Personalizados S. Tiago - Unidade de Saúde Familiar Amatus, Castelo Branco, PortugalUnidade de Cuidados de Saúde Personalizados Darque – ext Chafé, Viana do Castelo, PortugalUnidade Local de Saúde Castelo Branco, Castelo Branco, PortugalUnidade de Saúde Familiar Terra da Nóbrega, Vila Verde, PortugalUnidade de Cuidados de Saúde Personalizados Odemira, Odemira, PortugalUnidade de Saúde Familiar Gil Eanes, Viana do Castelo, PortugalUnidade de Cuidados de Saúde Personalizados S. Tiago - Unidade de Saúde Familiar Amatus, Castelo Branco, PortugalUnidade de Saúde Familiar Lethes, Ponte de Lima, PortugalUnidade de Saúde Familiar Lethes, Ponte de Lima, PortugalUnidade de Saúde Familiar Lethes, Ponte de Lima, PortugalUnidade de Saúde Familiar Lethes, Ponte de Lima, PortugalAim The REGENERAR registry study aimed to assess the prevalence of pain among Diabetic Peripheral Neuropathy (DPN) patients and to evaluate their health literacy and quality of life.Methods REGENERAR was a prospective, multicentric registry study conducted in primary healthcare units across Portugal. Adults with DPN were enrolled between April and September 2023. Sociodemographic and clinical information, including pain, neuropathic pain, literacy and quality of life were collected at inclusion visit (V1) and end-of-study visit (V2).Results The study enrolled 127 patients, 120 of whom completed V2. At V1, 77.5% of participants reported pain (61.7% at V2, p < 0.001), with neuropathic pain prevalence, assessed by clinical findings and result of DN4 questionnaire, being 48.3% at V1 and 46.7% at V2. Patient literacy on pain as a diabetes mellitus symptom improved from V1 to V2. Quality of life remained stable but suboptimal, with a median score of 70/100 on the EQ-5D-5L scale.Conclusion The REGENERAR registry highlights a high prevalence of pain among DPN patients in Portugal, exceeding international figures, but consistent with literature concerning neuropathic pain. It also identifies critical gaps in both patient and healthcare provider literacy. Addressing these gaps could improve disease management and quality of life.https://www.tandfonline.com/doi/10.1080/20565623.2025.2527503Neuropathic paindiabetic peripheral neuropathydiabetes mellitusquality of lifedisease literacy |
| spellingShingle | Filipe Antunes Emanuel Airosa Samara Rubio Rodriguez Igor Faria Diogo Anes Teresa Cruz José Miguel Oliveira João Simões Lisandra Dias Carina Faria Pedro Xavier Patrícia Alves Jacinta Pereira Inês Lima Raul Marques Pereira Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study Future Science OA Neuropathic pain diabetic peripheral neuropathy diabetes mellitus quality of life disease literacy |
| title | Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study |
| title_full | Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study |
| title_fullStr | Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study |
| title_full_unstemmed | Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study |
| title_short | Prevalence of pain and literacy in patients with diabetic peripheral neuropathy in Portugal: the REGENERAR registry study |
| title_sort | prevalence of pain and literacy in patients with diabetic peripheral neuropathy in portugal the regenerar registry study |
| topic | Neuropathic pain diabetic peripheral neuropathy diabetes mellitus quality of life disease literacy |
| url | https://www.tandfonline.com/doi/10.1080/20565623.2025.2527503 |
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