The Role of Antiviral Therapy for HBV-Related Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a highly prevalent and lethal cancer worldwide; despite the curative treatment for HCC, the rate of tumor recurrence after hepatectomy remains high. Tumor recurrence can occur early (<2 years) or late (>2 years) as metastases or de novo tumors. Several tumor f...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.4061/2011/416459 |
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| _version_ | 1849693006069760000 |
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| author | Liang-He Yu Nan Li Shu-Qun Cheng |
| author_facet | Liang-He Yu Nan Li Shu-Qun Cheng |
| author_sort | Liang-He Yu |
| collection | DOAJ |
| description | Hepatocellular carcinoma (HCC) is a highly prevalent and lethal cancer worldwide; despite the curative treatment for HCC, the rate of tumor recurrence after hepatectomy remains high. Tumor recurrence can occur early (<2 years) or late (>2 years) as metastases or de novo tumors. Several tumor factors were associated with HCC recurrence; high hepatitis B virus (HBV) load is the major risk factor for late recurrence of HCC after resection. Preoperative antiviral therapy improves liver function, and postoperative reduce HCC recurrence. In this paper, we focus on antiviral treatment to improve the liver function, prevent recurrence, and lengthen the overall survival for HBV-related HCC. |
| format | Article |
| id | doaj-art-95a184db40f94f5f9666a44a0eaa9ff0 |
| institution | DOAJ |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-95a184db40f94f5f9666a44a0eaa9ff02025-08-20T03:20:33ZengWileyInternational Journal of Hepatology2090-34482090-34562011-01-01201110.4061/2011/416459416459The Role of Antiviral Therapy for HBV-Related Hepatocellular CarcinomaLiang-He Yu0Nan Li1Shu-Qun Cheng2Eastern Hepatobiliary Surgery Hospital, The Second Military Medical University, Shanghai 200438, ChinaEastern Hepatobiliary Surgery Hospital, The Second Military Medical University, Shanghai 200438, ChinaEastern Hepatobiliary Surgery Hospital, The Second Military Medical University, Shanghai 200438, ChinaHepatocellular carcinoma (HCC) is a highly prevalent and lethal cancer worldwide; despite the curative treatment for HCC, the rate of tumor recurrence after hepatectomy remains high. Tumor recurrence can occur early (<2 years) or late (>2 years) as metastases or de novo tumors. Several tumor factors were associated with HCC recurrence; high hepatitis B virus (HBV) load is the major risk factor for late recurrence of HCC after resection. Preoperative antiviral therapy improves liver function, and postoperative reduce HCC recurrence. In this paper, we focus on antiviral treatment to improve the liver function, prevent recurrence, and lengthen the overall survival for HBV-related HCC.http://dx.doi.org/10.4061/2011/416459 |
| spellingShingle | Liang-He Yu Nan Li Shu-Qun Cheng The Role of Antiviral Therapy for HBV-Related Hepatocellular Carcinoma International Journal of Hepatology |
| title | The Role of Antiviral Therapy for HBV-Related Hepatocellular Carcinoma |
| title_full | The Role of Antiviral Therapy for HBV-Related Hepatocellular Carcinoma |
| title_fullStr | The Role of Antiviral Therapy for HBV-Related Hepatocellular Carcinoma |
| title_full_unstemmed | The Role of Antiviral Therapy for HBV-Related Hepatocellular Carcinoma |
| title_short | The Role of Antiviral Therapy for HBV-Related Hepatocellular Carcinoma |
| title_sort | role of antiviral therapy for hbv related hepatocellular carcinoma |
| url | http://dx.doi.org/10.4061/2011/416459 |
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