Exosomal novel-miRNA-126 mediates vascular endothelial dysfunction by targeting AhR-NLRP3 pathway in nonalcoholic steatohepatitis

Exosomal novel-miRNA-126 mediates vascular endothelial dysfunction by targeting AhR-NLRP3 pathway in nonalcoholic steatohepatitis

Abstract Nonalcoholic steatohepatitis (NASH) is an increasingly prevalent liver disease associated with obesity and its complications. Recent studies have underscored a significant correlation between NASH and an elevated risk of cardiovascular diseases. However, the precise mechanisms of inter-orga...

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Bibliographic Details
Main Authors: Qiuhe Chen, Lifeng Ye, Liting Huang, Hongjing You, Xiaoying Yu, Ke Wang, Shengtao Xiong, Weiyan Liao, Xiao Wang, Haiyan Li, Yang Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Non-alcoholic steatohepatitis (NASH)
Exosome
NLRP3
Endothelial dysfunction
Online Access:https://doi.org/10.1038/s41598-025-94917-y
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