Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and Ibuprofen

Enthalpies of solution and dilution of aqueous solutions of sodium acetylsalicylic acid salt and ibuprofen salt were measured with an isoperibolic calorimeter at 293.15 K, 298.15 K, 303.15 K, 308.15 K and 318.15 K. The concentration of the electrolyte was restricted to the solubility of the salt at...

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Main Authors: Juan Carlos Moreno-Piraján, Vanessa Silenia García-Cuello, Liliana Giraldo-Gutierréz
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/402395
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author Juan Carlos Moreno-Piraján
Vanessa Silenia García-Cuello
Liliana Giraldo-Gutierréz
author_facet Juan Carlos Moreno-Piraján
Vanessa Silenia García-Cuello
Liliana Giraldo-Gutierréz
author_sort Juan Carlos Moreno-Piraján
collection DOAJ
description Enthalpies of solution and dilution of aqueous solutions of sodium acetylsalicylic acid salt and ibuprofen salt were measured with an isoperibolic calorimeter at 293.15 K, 298.15 K, 303.15 K, 308.15 K and 318.15 K. The concentration of the electrolyte was restricted to the solubility of the salt at various temperatures and did not exceed 0.035–0.057 mol kg-1, depending on the temperature studied. The Virial coefficients were derived from Pitzer's model and the excess thermodynamic functions of both the solution and the components of the solution were calculated. An analysis of the thermodynamic characteristics of the solution in terms of concentration and temperature interval was carried out and discussed. Additionally, an analysis was performed by differential scanning calorimetry (DSC).
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institution Kabale University
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publishDate 2011-01-01
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series E-Journal of Chemistry
spelling doaj-art-958b14968f2c4a2e80a09c6515f714972025-08-20T03:37:02ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-01831298130810.1155/2011/402395Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and IbuprofenJuan Carlos Moreno-Piraján0Vanessa Silenia García-Cuello1Liliana Giraldo-Gutierréz2Grupo de Investigación en Sólidos Porosos y Calorimetría, Departamento de Química, Universidad de los Andes, Carrera 1 No 18 A 10, Bogotá, ColombiaGrupo de Investigación en Sólidos Porosos y Calorimetría, Departamento de Química, Universidad de los Andes, Carrera 1 No 18 A 10, Bogotá, ColombiaFacultad de Ciencias, Departamento de Química, Universidad Nacional de Colombia, Carrera 30 No 45-03, Bogotá, ColombiaEnthalpies of solution and dilution of aqueous solutions of sodium acetylsalicylic acid salt and ibuprofen salt were measured with an isoperibolic calorimeter at 293.15 K, 298.15 K, 303.15 K, 308.15 K and 318.15 K. The concentration of the electrolyte was restricted to the solubility of the salt at various temperatures and did not exceed 0.035–0.057 mol kg-1, depending on the temperature studied. The Virial coefficients were derived from Pitzer's model and the excess thermodynamic functions of both the solution and the components of the solution were calculated. An analysis of the thermodynamic characteristics of the solution in terms of concentration and temperature interval was carried out and discussed. Additionally, an analysis was performed by differential scanning calorimetry (DSC).http://dx.doi.org/10.1155/2011/402395
spellingShingle Juan Carlos Moreno-Piraján
Vanessa Silenia García-Cuello
Liliana Giraldo-Gutierréz
Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and Ibuprofen
E-Journal of Chemistry
title Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and Ibuprofen
title_full Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and Ibuprofen
title_fullStr Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and Ibuprofen
title_full_unstemmed Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and Ibuprofen
title_short Thermodynamic and Calorimetric Study of Acetylsalicylic Acid (Aspirin) and Ibuprofen
title_sort thermodynamic and calorimetric study of acetylsalicylic acid aspirin and ibuprofen
url http://dx.doi.org/10.1155/2011/402395
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AT vanessasileniagarciacuello thermodynamicandcalorimetricstudyofacetylsalicylicacidaspirinandibuprofen
AT lilianagiraldogutierrez thermodynamicandcalorimetricstudyofacetylsalicylicacidaspirinandibuprofen