Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids
Recently, fabrication of organic-inorganic hybrid biomedical materials using biomimetic mineralization processes has received attention because it proceeds under mild conditions and biocompatible inorganic components are incorporated in the resulting hybrids. In the present study, the preparation of...
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| Format: | Article |
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Taylor & Francis Group
2024-12-01
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| Series: | Journal of Asian Ceramic Societies |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21870764.2024.2445444 |
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| author | Takuya Sagawa Noritaka Kako Masatoshi Nakaya Takaaki Izumi Kosuke Takeda Kazutoshi Iijima Mineo Hashizume |
| author_facet | Takuya Sagawa Noritaka Kako Masatoshi Nakaya Takaaki Izumi Kosuke Takeda Kazutoshi Iijima Mineo Hashizume |
| author_sort | Takuya Sagawa |
| collection | DOAJ |
| description | Recently, fabrication of organic-inorganic hybrid biomedical materials using biomimetic mineralization processes has received attention because it proceeds under mild conditions and biocompatible inorganic components are incorporated in the resulting hybrids. In the present study, the preparation of anionic polyelectrolyte-apatite hybrids, having potential as a biomedical material, in simulated body fluids (SBFs) was performed. Anionic polyelectrolytes such as heparin, poly(4-styrene sulfonate) (PSS), or poly(vinyl sulfate) (PVS) were added to SBFs and incubated to induce nucleation of hydroxyapatite, which resulted in the formation of anionic polyelectrolyte-apatite hybrids. Physical characterization of the resulting deposits in SBFs using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), FT-IR spectroscopy, and X-ray diffraction (XRD) revealed that the polyelectrolyte concentration affected the yield of the resulting deposits. It seemed that the reaction condition affected the apatite nucleation process in SBFs. Effect of chemical structures and concentrations of anionic polyelectrolytes on hybrid formation is discussed. |
| format | Article |
| id | doaj-art-958ab9ad0ac44e1cad075abe0f116cd6 |
| institution | OA Journals |
| issn | 2187-0764 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Asian Ceramic Societies |
| spelling | doaj-art-958ab9ad0ac44e1cad075abe0f116cd62025-08-20T02:32:00ZengTaylor & Francis GroupJournal of Asian Ceramic Societies2187-07642024-12-011910.1080/21870764.2024.2445444Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluidsTakuya Sagawa0Noritaka Kako1Masatoshi Nakaya2Takaaki Izumi3Kosuke Takeda4Kazutoshi Iijima5Mineo Hashizume6Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, JapanDepartment of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, JapanDepartment of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, JapanDepartment of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, JapanDepartment of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, JapanDepartment of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, JapanDepartment of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, JapanRecently, fabrication of organic-inorganic hybrid biomedical materials using biomimetic mineralization processes has received attention because it proceeds under mild conditions and biocompatible inorganic components are incorporated in the resulting hybrids. In the present study, the preparation of anionic polyelectrolyte-apatite hybrids, having potential as a biomedical material, in simulated body fluids (SBFs) was performed. Anionic polyelectrolytes such as heparin, poly(4-styrene sulfonate) (PSS), or poly(vinyl sulfate) (PVS) were added to SBFs and incubated to induce nucleation of hydroxyapatite, which resulted in the formation of anionic polyelectrolyte-apatite hybrids. Physical characterization of the resulting deposits in SBFs using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), FT-IR spectroscopy, and X-ray diffraction (XRD) revealed that the polyelectrolyte concentration affected the yield of the resulting deposits. It seemed that the reaction condition affected the apatite nucleation process in SBFs. Effect of chemical structures and concentrations of anionic polyelectrolytes on hybrid formation is discussed.https://www.tandfonline.com/doi/10.1080/21870764.2024.2445444HydroxyapatiteAnionic polyelectrolyteSimulated body fluidOrganic-inorganic hybrid |
| spellingShingle | Takuya Sagawa Noritaka Kako Masatoshi Nakaya Takaaki Izumi Kosuke Takeda Kazutoshi Iijima Mineo Hashizume Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids Journal of Asian Ceramic Societies Hydroxyapatite Anionic polyelectrolyte Simulated body fluid Organic-inorganic hybrid |
| title | Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids |
| title_full | Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids |
| title_fullStr | Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids |
| title_full_unstemmed | Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids |
| title_short | Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids |
| title_sort | effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids |
| topic | Hydroxyapatite Anionic polyelectrolyte Simulated body fluid Organic-inorganic hybrid |
| url | https://www.tandfonline.com/doi/10.1080/21870764.2024.2445444 |
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