The immunological perspective of major depressive disorder: unveiling the interactions between central and peripheral immune mechanisms

The immunological perspective of major depressive disorder: unveiling the interactions between central and peripheral immune mechanisms

Abstract Major depressive disorder is a prevalent mental disorder, yet its pathogenesis remains poorly understood. Accumulating evidence implicates dysregulated immune mechanisms as key contributors to depressive disorders. This review elucidates the complex interplay between peripheral and central...

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Bibliographic Details
Main Authors: Wenli Jiao, Jiayi Lin, Yanfang Deng, Yelin Ji, Chuoyi Liang, Sijia Wei, Xi Jing, Fengxia Yan
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Neuroinflammation
Subjects:
Major depressive disorder
Neuroimmune interactions
Neuroinflammation
Peripheral-central crosstalk
Online Access:https://doi.org/10.1186/s12974-024-03312-3
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