Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”?
Glyphosate (GLY) is the most widely used herbicide worldwide, and its use continues to increase. Accumulating evidence shows that GLY and its metabolite aminomethylphosphonic acid (AMPA) are more persistent and toxic than expected, but little is known about the risks to wildlife. Glufosinate (GLUF)...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Peer Community In
2025-01-01
|
| Series: | Peer Community Journal |
| Subjects: | |
| Online Access: | https://peercommunityjournal.org/articles/10.24072/pcjournal.509/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825206352715186176 |
|---|---|
| author | Fritsch, Clémentine Appenzeller, Brice M. R. Bertrand, Colette Coeurdassier, Michael Driget, Vincent Hardy, Emilie M Palazzi, Paul Schaeffer, Charline Goydadin, Anne-Claude Gaba, Sabrina Bretagnolle, Vincent Pelosi, Céline |
| author_facet | Fritsch, Clémentine Appenzeller, Brice M. R. Bertrand, Colette Coeurdassier, Michael Driget, Vincent Hardy, Emilie M Palazzi, Paul Schaeffer, Charline Goydadin, Anne-Claude Gaba, Sabrina Bretagnolle, Vincent Pelosi, Céline |
| author_sort | Fritsch, Clémentine |
| collection | DOAJ |
| description | Glyphosate (GLY) is the most widely used herbicide worldwide, and its use continues to increase. Accumulating evidence shows that GLY and its metabolite aminomethylphosphonic acid (AMPA) are more persistent and toxic than expected, but little is known about the risks to wildlife. Glufosinate (GLUF) was considered an alternative broad-spectrum herbicide, but its field ecotoxicology has rarely been studied. This study aimed to assess the exposure of free-ranging rodents and shrews from treated (cereals under conventional farming) and nontreated habitats (cereals under organic farming and hedgerows) in France to GLY, AMPA, and GLUF through residue analyses in hair. We investigated the patterns of accumulation according to species, habitat, and treatment intensity at the plot, landscape, or township scale. We showed a generalized exposure of small mammals to GLY, AMPA and GLUF, as they were detected in all of the species, and in 64%, 51% and 44% of the hair samples, respectively. The detection and levels of GLY, AMPA and GLUF were greater in herbivorous and omnivorous voles than in insectivorous shrews and omnivorous wild mice. The three compounds showed comparable ranges of concentrations: 0.018-7.74 pg/mg with an outlier of 522 pg/mg for GLY (median = 2.65 pg/mg), 0.240-33.6 pg/mg for AMPA (median = 1.39 pg/mg), and 1.16-25.5 pg/mg for GLUF (median = 3.51 pg/mg). The frequencies of detection and concentrations did not significantly differ according to the farming practices or proxies of pesticide treatment intensity. The concentrations of GLY were greater in individuals captured in hedgerows than in those captured in cereal fields. On the basis of dose reconstruction approaches and toxicological thresholds from the literature, GLY and GLUF levels may be associated with risk in small mammals and endanger local populations. Our findings raise issues about the omnipresence of GLY, AMPA and GLUF in agricultural landscapes, including in animals from habitats considered refuges, questioning their ecological safety. This work provides new insights into current broad-spectrum herbicide wildlife ecotoxicology that may support decision-making to protect biodiversity. |
| format | Article |
| id | doaj-art-95854fe8dbcc4f5984efe711afa3e6b5 |
| institution | Kabale University |
| issn | 2804-3871 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Peer Community In |
| record_format | Article |
| series | Peer Community Journal |
| spelling | doaj-art-95854fe8dbcc4f5984efe711afa3e6b52025-02-07T10:34:51ZengPeer Community InPeer Community Journal2804-38712025-01-01510.24072/pcjournal.50910.24072/pcjournal.509Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”? Fritsch, Clémentine0https://orcid.org/0000-0003-2062-5799Appenzeller, Brice M. R.1https://orcid.org/0000-0001-9021-929XBertrand, Colette2https://orcid.org/0000-0003-0599-3331Coeurdassier, Michael3https://orcid.org/0000-0002-6260-311XDriget, Vincent4Hardy, Emilie M5Palazzi, Paul6Schaeffer, Charline7Goydadin, Anne-Claude8Gaba, Sabrina9https://orcid.org/0000-0002-7145-6713Bretagnolle, Vincent10https://orcid.org/0000-0002-2320-7755Pelosi, Céline11https://orcid.org/0000-0002-7100-5760Laboratoire Chrono-environnement (UMR 6249 CNRS, Université Marie et Louis Pasteur, Université de Franche-Comté) - Besançon, FranceLuxembourg Institute of Health - Strassen, LuxembourgEcologie fonctionnelle et écotoxicologie des agroécosystèmes (UMR 1402, AgroParisTech, Université Paris-Saclay, INRAE) - Palaiseau, FranceLaboratoire Chrono-environnement (UMR 6249 CNRS, Université Marie et Louis Pasteur, Université de Franche-Comté) - Besançon, FranceLaboratoire Chrono-environnement (UMR 6249 CNRS, Université Marie et Louis Pasteur, Université de Franche-Comté) - Besançon, FranceLuxembourg Institute of Health - Strassen, LuxembourgLuxembourg Institute of Health - Strassen, LuxembourgLuxembourg Institute of Health - Strassen, LuxembourgLaboratoire Chrono-environnement (UMR 6249 CNRS, Université Marie et Louis Pasteur, Université de Franche-Comté) - Besançon, FranceCentre d’Études Biologiques de Chizé (UMR 7372 CNRS, La Rochelle Université, USC INRAE) - Villiers-en-Bois, France; Zone Atelier Plaine et Val de Sèvre - Villiers-en-Bois, FranceCentre d’Études Biologiques de Chizé (UMR 7372 CNRS, La Rochelle Université, USC INRAE) - Villiers-en-Bois, France; Zone Atelier Plaine et Val de Sèvre - Villiers-en-Bois, FranceEcologie fonctionnelle et écotoxicologie des agroécosystèmes (UMR 1402, AgroParisTech, Université Paris-Saclay, INRAE) - Palaiseau, France; Environnement Méditerranéen et Modélisation des Agro-Hydrosystèmes (UMR 1114, INRAE Domaine Saint-Paul, Avignon Université) - Avignon, FranceGlyphosate (GLY) is the most widely used herbicide worldwide, and its use continues to increase. Accumulating evidence shows that GLY and its metabolite aminomethylphosphonic acid (AMPA) are more persistent and toxic than expected, but little is known about the risks to wildlife. Glufosinate (GLUF) was considered an alternative broad-spectrum herbicide, but its field ecotoxicology has rarely been studied. This study aimed to assess the exposure of free-ranging rodents and shrews from treated (cereals under conventional farming) and nontreated habitats (cereals under organic farming and hedgerows) in France to GLY, AMPA, and GLUF through residue analyses in hair. We investigated the patterns of accumulation according to species, habitat, and treatment intensity at the plot, landscape, or township scale. We showed a generalized exposure of small mammals to GLY, AMPA and GLUF, as they were detected in all of the species, and in 64%, 51% and 44% of the hair samples, respectively. The detection and levels of GLY, AMPA and GLUF were greater in herbivorous and omnivorous voles than in insectivorous shrews and omnivorous wild mice. The three compounds showed comparable ranges of concentrations: 0.018-7.74 pg/mg with an outlier of 522 pg/mg for GLY (median = 2.65 pg/mg), 0.240-33.6 pg/mg for AMPA (median = 1.39 pg/mg), and 1.16-25.5 pg/mg for GLUF (median = 3.51 pg/mg). The frequencies of detection and concentrations did not significantly differ according to the farming practices or proxies of pesticide treatment intensity. The concentrations of GLY were greater in individuals captured in hedgerows than in those captured in cereal fields. On the basis of dose reconstruction approaches and toxicological thresholds from the literature, GLY and GLUF levels may be associated with risk in small mammals and endanger local populations. Our findings raise issues about the omnipresence of GLY, AMPA and GLUF in agricultural landscapes, including in animals from habitats considered refuges, questioning their ecological safety. This work provides new insights into current broad-spectrum herbicide wildlife ecotoxicology that may support decision-making to protect biodiversity.https://peercommunityjournal.org/articles/10.24072/pcjournal.509/Agro-ecosystem, Bioaccumulation, Currently used pesticides, Landscape ecotoxicology, Wildlife toxicology |
| spellingShingle | Fritsch, Clémentine Appenzeller, Brice M. R. Bertrand, Colette Coeurdassier, Michael Driget, Vincent Hardy, Emilie M Palazzi, Paul Schaeffer, Charline Goydadin, Anne-Claude Gaba, Sabrina Bretagnolle, Vincent Pelosi, Céline Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”? Peer Community Journal Agro-ecosystem, Bioaccumulation, Currently used pesticides, Landscape ecotoxicology, Wildlife toxicology |
| title | Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”?
|
| title_full | Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”?
|
| title_fullStr | Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”?
|
| title_full_unstemmed | Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”?
|
| title_short | Exposure of wild mammals to glyphosate, AMPA, and glufosinate: a case for “emerging organic contaminants”?
|
| title_sort | exposure of wild mammals to glyphosate ampa and glufosinate a case for emerging organic contaminants |
| topic | Agro-ecosystem, Bioaccumulation, Currently used pesticides, Landscape ecotoxicology, Wildlife toxicology |
| url | https://peercommunityjournal.org/articles/10.24072/pcjournal.509/ |
| work_keys_str_mv | AT fritschclementine exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT appenzellerbricemr exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT bertrandcolette exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT coeurdassiermichael exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT drigetvincent exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT hardyemiliem exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT palazzipaul exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT schaeffercharline exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT goydadinanneclaude exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT gabasabrina exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT bretagnollevincent exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants AT pelosiceline exposureofwildmammalstoglyphosateampaandglufosinateacaseforemergingorganiccontaminants |