Transdermal Semaglutide Administration in Mice: Reduces Body Weight by Suppressing Appetite and Enhancing Metabolic Rate

Transdermal Semaglutide Administration in Mice: Reduces Body Weight by Suppressing Appetite and Enhancing Metabolic Rate

Background: Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that shows significant efficacy in treating obesity. However, its associated side effects, including poor patient compliance and gastrointestinal inflammation, are concerning and may be largely attributed to its administra...

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Bibliographic Details
Main Authors: Wenjing Li, Ruilin Cai, Binxin Yin, Yingying Zhou, Xinyuan Dong, Wenting Li, Jing Wen
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biology
Subjects:
GLP-1RA
transdermal
body weight
metabolic rate
anxiety-like behavior
Online Access:https://www.mdpi.com/2079-7737/14/5/575
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