Whole genome sequence analysis reveals limited diversity among Clostridioides difficile ribotype 027 and 078 isolates collected in 22 hospitals in Berlin and Brandenburg, Germany

Whole genome sequence analysis reveals limited diversity among Clostridioides difficile ribotype 027 and 078 isolates collected in 22 hospitals in Berlin and Brandenburg, Germany

Abstract Background Clostridioides difficile infections (CDI) present significant health risks and are among the most important nosocomial infections. Ribotype (RT) 027 poses a particular risk due to its proposed “hypervirulence”. Traditionally, C. difficile isolates are characterized using PCR-ribo...

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Bibliographic Details
Main Authors: Esther E. Dirks, Vanessa Pfiffer, Genevieve Sohl, Fabian K. Berger, Ina Friesen, Johannes Friesen, Ralf Ignatius, Johannes Elias, Alexander Mellmann, Mardjan Arvand
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Clostridioides difficile
Ribotype 027
Ribotype 078
Clostridioides difficile infection (CDI)
Whole genome sequencing (WGS)
Ribotyping
Online Access:https://doi.org/10.1186/s13756-025-01565-y
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