Safety and efficacy of a feed additive consisting of β‐mannanase produced by Aspergillus niger CBS 120604 (Nutrixtend Optim) for use in all poultry for fattening (Kerry Ingredients & Flavours Ltd)

Safety and efficacy of a feed additive consisting of β‐mannanase produced by Aspergillus niger CBS 120604 (Nutrixtend Optim) for use in all poultry for fattening (Kerry Ingredients & Flavours Ltd)

Abstract Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of a product containing β‐mannanase produced by a non‐genetically modified strain of Asp...

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Main Authors: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Giovanna Martelli, Luca Tosti, Montserrat Anguita, Yolanda García‐Cazorla, Elisa Pettenati, Jordi Ortuño
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:EFSA Journal
Subjects:
zootechnical additives
digestibility enhancers
β‐Mannanase
safety
efficacy
poultry for fattening
Online Access:https://doi.org/10.2903/j.efsa.2023.8045
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Summary:Abstract Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of a product containing β‐mannanase produced by a non‐genetically modified strain of Aspergillus niger (CBS 120604). The commercial name is Nutrixtend Optim and it is intended to be used as a zootechnical feed additive for all poultry for fattening. Based on a tolerance trial in chickens for fattening and the no observed adverse effect level identified in a subchronic oral toxicity study in rats, the additive was considered safe for all poultry for fattening. The Panel concluded that the use of the product as a feed additive does not give rise to concerns for consumers and the environment. The additive is considered an irritant to skin and eyes and a dermal sensitiser. Due to the proteinaceous nature of the active substance, it is also considered a respiratory sensitiser. The Panel concludes that the additive has the potential to be efficacious as a zootechnical additive at the level of inclusion in feed of chickens for fattening of 30 U β‐mannanase/kg complete feed. This conclusion was extrapolated to all poultry for fattening.
ISSN:1831-4732

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