Association between statin administration and outcome in patients with sepsis: A retrospective study

There was considerable debate regarding the effect of statins administration on the outcome of septic patients. This retrospective study aimed to assess the association between statins administration and mortality in sepsis patients and investigate whether this association differed according to the...

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Main Authors: Zhou Jianzhu, Feng Zeying, Qiu Hui, Li Tong, Huang Xin, Ye Ling, Huang Longjian, Guo Chengjun, Guo Chengxian, He Li
Format: Article
Language:English
Published: De Gruyter 2025-02-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2024-1112
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author Zhou Jianzhu
Feng Zeying
Qiu Hui
Li Tong
Huang Xin
Ye Ling
Huang Longjian
Guo Chengjun
Guo Chengxian
He Li
author_facet Zhou Jianzhu
Feng Zeying
Qiu Hui
Li Tong
Huang Xin
Ye Ling
Huang Longjian
Guo Chengjun
Guo Chengxian
He Li
author_sort Zhou Jianzhu
collection DOAJ
description There was considerable debate regarding the effect of statins administration on the outcome of septic patients. This retrospective study aimed to assess the association between statins administration and mortality in sepsis patients and investigate whether this association differed according to the types of statins.
format Article
id doaj-art-95547d33fbd94ed480e5ff85d8dcf172
institution Kabale University
issn 2391-5463
language English
publishDate 2025-02-01
publisher De Gruyter
record_format Article
series Open Medicine
spelling doaj-art-95547d33fbd94ed480e5ff85d8dcf1722025-02-10T13:24:39ZengDe GruyterOpen Medicine2391-54632025-02-01201118124710.1515/med-2024-1112Association between statin administration and outcome in patients with sepsis: A retrospective studyZhou Jianzhu0Feng Zeying1Qiu Hui2Li Tong3Huang Xin4Ye Ling5Huang Longjian6Guo Chengjun7Guo Chengxian8He Li9Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, ChinaCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, ChinaCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, ChinaCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, ChinaCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, ChinaCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, ChinaWest Guangxi Key Laboratory for Prevention and Treatment of High-Incidence Diseases, Youjiang Medical University for Nationalities, Baise, 533000, Guangxi, ChinaSchool of Applied Mathematics, Guangdong University of Technology, Guangzhou, 510006, Guangdong, ChinaCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, ChinaDepartment of Pediatrics, the Third Xiangya Hospital of Central South University, Changsha, 410013, Hunan, ChinaThere was considerable debate regarding the effect of statins administration on the outcome of septic patients. This retrospective study aimed to assess the association between statins administration and mortality in sepsis patients and investigate whether this association differed according to the types of statins.https://doi.org/10.1515/med-2024-1112sepsisstatinatorvastatinmortalityintensive care unit
spellingShingle Zhou Jianzhu
Feng Zeying
Qiu Hui
Li Tong
Huang Xin
Ye Ling
Huang Longjian
Guo Chengjun
Guo Chengxian
He Li
Association between statin administration and outcome in patients with sepsis: A retrospective study
Open Medicine
sepsis
statin
atorvastatin
mortality
intensive care unit
title Association between statin administration and outcome in patients with sepsis: A retrospective study
title_full Association between statin administration and outcome in patients with sepsis: A retrospective study
title_fullStr Association between statin administration and outcome in patients with sepsis: A retrospective study
title_full_unstemmed Association between statin administration and outcome in patients with sepsis: A retrospective study
title_short Association between statin administration and outcome in patients with sepsis: A retrospective study
title_sort association between statin administration and outcome in patients with sepsis a retrospective study
topic sepsis
statin
atorvastatin
mortality
intensive care unit
url https://doi.org/10.1515/med-2024-1112
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