Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image Registration

Background: Retinal imaging employs various modalities, each providing distinct perspectives on ocular structures. However, the integration of information from these modalities, which often have differing resolutions, requires effective image registration techniques. Existing retinal image registrat...

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Main Authors: Monire Sheikh Hosseini, Hossein Rabbani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Journal of Medical Signals and Sensors
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Online Access:https://journals.lww.com/jmss/fulltext/2025/05010/nonrigid_multimodal_registration_based_on_fuzzy.1.aspx
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author Monire Sheikh Hosseini
Hossein Rabbani
author_facet Monire Sheikh Hosseini
Hossein Rabbani
author_sort Monire Sheikh Hosseini
collection DOAJ
description Background: Retinal imaging employs various modalities, each providing distinct perspectives on ocular structures. However, the integration of information from these modalities, which often have differing resolutions, requires effective image registration techniques. Existing retinal image registration methods typically rely on rigid or affine transformations, which may not adequately address the complexities of multimodal retinal images. Method: This study introduces a nonrigid fuzzy image registration approach designed to align optical coherence tomography (OCT) images with fundus images. The method employs a fuzzy inference system (FIS) that uses vessel locations as key features for registration. The FIS applies specific rules to map points from the source image to the reference image, facilitating accurate alignment. Results: The proposed method achieved a mean absolute registration error of 44.57 ± 39.38 µm in the superior–inferior orientation and 11.46 ± 10.06 µm in the nasal-temporal orientation. These results underscore the method’s precision in aligning multimodal retinal images. Conclusion: The nonrigid fuzzy image registration approach demonstrates robust and versatile performance in integrating multimodal retinal imaging data. Despite its straightforward implementation, the method effectively addresses the challenges of multimodal retinal image registration, providing a reliable tool for advanced ocular imaging analysis.
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spelling doaj-art-9551cf41721a4e058e52d3d1c4e287fb2025-08-20T03:16:28ZengWolters Kluwer Medknow PublicationsJournal of Medical Signals and Sensors2228-74772025-05-01155131310.4103/jmss.jmss_42_24Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image RegistrationMonire Sheikh HosseiniHossein RabbaniBackground: Retinal imaging employs various modalities, each providing distinct perspectives on ocular structures. However, the integration of information from these modalities, which often have differing resolutions, requires effective image registration techniques. Existing retinal image registration methods typically rely on rigid or affine transformations, which may not adequately address the complexities of multimodal retinal images. Method: This study introduces a nonrigid fuzzy image registration approach designed to align optical coherence tomography (OCT) images with fundus images. The method employs a fuzzy inference system (FIS) that uses vessel locations as key features for registration. The FIS applies specific rules to map points from the source image to the reference image, facilitating accurate alignment. Results: The proposed method achieved a mean absolute registration error of 44.57 ± 39.38 µm in the superior–inferior orientation and 11.46 ± 10.06 µm in the nasal-temporal orientation. These results underscore the method’s precision in aligning multimodal retinal images. Conclusion: The nonrigid fuzzy image registration approach demonstrates robust and versatile performance in integrating multimodal retinal imaging data. Despite its straightforward implementation, the method effectively addresses the challenges of multimodal retinal image registration, providing a reliable tool for advanced ocular imaging analysis.https://journals.lww.com/jmss/fulltext/2025/05010/nonrigid_multimodal_registration_based_on_fuzzy.1.aspxfundusfuzzymultimodal registrationnonrigid image registrationoptical coherence tomography
spellingShingle Monire Sheikh Hosseini
Hossein Rabbani
Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image Registration
Journal of Medical Signals and Sensors
fundus
fuzzy
multimodal registration
nonrigid image registration
optical coherence tomography
title Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image Registration
title_full Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image Registration
title_fullStr Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image Registration
title_full_unstemmed Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image Registration
title_short Nonrigid Multimodal Registration Based on Fuzzy Inference System for Retinal Image Registration
title_sort nonrigid multimodal registration based on fuzzy inference system for retinal image registration
topic fundus
fuzzy
multimodal registration
nonrigid image registration
optical coherence tomography
url https://journals.lww.com/jmss/fulltext/2025/05010/nonrigid_multimodal_registration_based_on_fuzzy.1.aspx
work_keys_str_mv AT moniresheikhhosseini nonrigidmultimodalregistrationbasedonfuzzyinferencesystemforretinalimageregistration
AT hosseinrabbani nonrigidmultimodalregistrationbasedonfuzzyinferencesystemforretinalimageregistration