Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan

Contrast-enhanced mammography (CEM) has emerged as a promising technology in the field of breast imaging, experiencing growing acceptance. However, the comparative evaluation of its diagnostic accuracy against MRI remains sparse, largely attributed to its relatively recent introduction. Current stud...

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Main Authors: Roya Faghani, MD, Sahar Darabi Monadi, MD, Vasiliki Papalouka, MD, Tamara Suaris, MD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S193004332500473X
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author Roya Faghani, MD
Sahar Darabi Monadi, MD
Vasiliki Papalouka, MD
Tamara Suaris, MD
author_facet Roya Faghani, MD
Sahar Darabi Monadi, MD
Vasiliki Papalouka, MD
Tamara Suaris, MD
author_sort Roya Faghani, MD
collection DOAJ
description Contrast-enhanced mammography (CEM) has emerged as a promising technology in the field of breast imaging, experiencing growing acceptance. However, the comparative evaluation of its diagnostic accuracy against MRI remains sparse, largely attributed to its relatively recent introduction. Current studies suggest that MRI and CEM exhibit comparable sensitivity for detecting the index breast lesion. However, there is conflicting evidence regarding their sensitivity in detecting additional breast lesions in cases of known breast cancer, with some studies demonstrating MRI's superiority and others reporting similar sensitivity between the 2 modalities. We present a case where CEM effectively detected a contralateral breast malignancy in a patient with a newly diagnosed breast cancer, whereas it went undetected by MRI initially. Our presentation underscores the importance of more comprehensive research to assess CEM's overall diagnostic capabilities in breast imaging in comparison to MRI, as there may be situations where CEM outperforms MRI.
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issn 1930-0433
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publishDate 2025-09-01
publisher Elsevier
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series Radiology Case Reports
spelling doaj-art-954d00c03a5543d2a73f66628cfdc0242025-08-20T03:17:03ZengElsevierRadiology Case Reports1930-04332025-09-012094275428510.1016/j.radcr.2025.05.046Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scanRoya Faghani, MD0Sahar Darabi Monadi, MD1Vasiliki Papalouka, MD2Tamara Suaris, MD3Breast Radiology, Barts Health NHS Trust, London, UKCardiology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK; Corresponding author.Breast Radiology, Barts Health NHS Trust, London, UKBreast Radiology, Barts Health NHS Trust, London, UKContrast-enhanced mammography (CEM) has emerged as a promising technology in the field of breast imaging, experiencing growing acceptance. However, the comparative evaluation of its diagnostic accuracy against MRI remains sparse, largely attributed to its relatively recent introduction. Current studies suggest that MRI and CEM exhibit comparable sensitivity for detecting the index breast lesion. However, there is conflicting evidence regarding their sensitivity in detecting additional breast lesions in cases of known breast cancer, with some studies demonstrating MRI's superiority and others reporting similar sensitivity between the 2 modalities. We present a case where CEM effectively detected a contralateral breast malignancy in a patient with a newly diagnosed breast cancer, whereas it went undetected by MRI initially. Our presentation underscores the importance of more comprehensive research to assess CEM's overall diagnostic capabilities in breast imaging in comparison to MRI, as there may be situations where CEM outperforms MRI.http://www.sciencedirect.com/science/article/pii/S193004332500473XContrast-enhanced mammography (CEM)MRIBreast cancer
spellingShingle Roya Faghani, MD
Sahar Darabi Monadi, MD
Vasiliki Papalouka, MD
Tamara Suaris, MD
Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan
Radiology Case Reports
Contrast-enhanced mammography (CEM)
MRI
Breast cancer
title Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan
title_full Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan
title_fullStr Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan
title_full_unstemmed Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan
title_short Detection of a contralateral breast malignancy using contrast-enhanced mammography (CEM) overlooked by initial MRI scan
title_sort detection of a contralateral breast malignancy using contrast enhanced mammography cem overlooked by initial mri scan
topic Contrast-enhanced mammography (CEM)
MRI
Breast cancer
url http://www.sciencedirect.com/science/article/pii/S193004332500473X
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