Evaluation of biocompatibility, antimicrobial activity, and immunomodulatory effects of mineral trioxide aggregate modified with zeolite-clinoptilolite as a root-end filling material

Evaluation of biocompatibility, antimicrobial activity, and immunomodulatory effects of mineral trioxide aggregate modified with zeolite-clinoptilolite as a root-end filling material

Abstract Objective This study aimed to evaluate the in vitro toxicity of commercially available mineral trioxide aggregate (MTA) and various MTA modified cement types on a human fibroblast cell line. Additionally, the antibacterial and immunomodulatory properties of the modified cements were investi...

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Bibliographic Details
Main Authors: Stefan Velickovic, Sladjana Pavlovic, Bojana Simovic Markovic, Ivan Jovanovic, Sanja Zornic, Milan Kragovic, Radmila Lisanin, Marko Milosavljevic, Rasa Mladenovic, Aleksandra Misic, Vladimir S. Todorovic, Miroslav Vasovic
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
Subjects:
Root-end filling material
Biocompatibility
Antimicrobial activity
Immunomodulatory effects
Mineral trioxide aggregate
Zeolite
Online Access:https://doi.org/10.1186/s12903-025-06587-x
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