Use of neuromodulators in the treatment of irritable bowel syndrome
Irritable bowel syndrome (IBS) is the prevalent functional gastrointestinal disorder. In most patients, it is combined with mental and psychological abnormalities and results in a considerable decline in quality of life. The precise etiology of IBS is still unknown, but it may be related to gastroin...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of New Medicine
2021-12-01
|
| Series: | Yixue xinzhi zazhi |
| Subjects: | |
| Online Access: | https://yxxz.whuznhmedj.com/storage/attach/2112/epcbCIktARMbxEwYcb212jnulKbkfvKw8Fr3fpU0.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850098746425081856 |
|---|---|
| author | Jing-Jing HU Jin-Song LIU |
| author_facet | Jing-Jing HU Jin-Song LIU |
| author_sort | Jing-Jing HU |
| collection | DOAJ |
| description | Irritable bowel syndrome (IBS) is the prevalent functional gastrointestinal disorder. In most patients, it is combined with mental and psychological abnormalities and results in a considerable decline in quality of life. The precise etiology of IBS is still unknown, but it may be related to gastrointestinal motility abnormalities, visceral hypersensitivity, mucosal immunity abnormalities, alteration of intestinal flora and gut-brain axis abnormalities. Traditional drugs have been less effective in treating IBS. The neuromodulators, including tricyclic antidepressants and selective serotonin reuptake inhibitors, can not only moderate pain sensation, reduce visceral hypersensitivity, regulate gastrointestinal motility and improve symptoms, but also treat patients associated with mental and psychological abnormalities. In this paper, the application of neuromodulators in the treatment of IBS is briefly reviewed. |
| format | Article |
| id | doaj-art-9540545993d34bb7af7d4861298b3a40 |
| institution | DOAJ |
| issn | 1004-5511 |
| language | zho |
| publishDate | 2021-12-01 |
| publisher | Editorial Office of New Medicine |
| record_format | Article |
| series | Yixue xinzhi zazhi |
| spelling | doaj-art-9540545993d34bb7af7d4861298b3a402025-08-20T02:40:39ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112021-12-0131646046510.12173/j.issn.1004-5511.2021030226266Use of neuromodulators in the treatment of irritable bowel syndromeJing-Jing HUJin-Song LIUIrritable bowel syndrome (IBS) is the prevalent functional gastrointestinal disorder. In most patients, it is combined with mental and psychological abnormalities and results in a considerable decline in quality of life. The precise etiology of IBS is still unknown, but it may be related to gastrointestinal motility abnormalities, visceral hypersensitivity, mucosal immunity abnormalities, alteration of intestinal flora and gut-brain axis abnormalities. Traditional drugs have been less effective in treating IBS. The neuromodulators, including tricyclic antidepressants and selective serotonin reuptake inhibitors, can not only moderate pain sensation, reduce visceral hypersensitivity, regulate gastrointestinal motility and improve symptoms, but also treat patients associated with mental and psychological abnormalities. In this paper, the application of neuromodulators in the treatment of IBS is briefly reviewed.https://yxxz.whuznhmedj.com/storage/attach/2112/epcbCIktARMbxEwYcb212jnulKbkfvKw8Fr3fpU0.pdfirritable bowel syndrome neuromodulator mental and psychological abnormality treatment |
| spellingShingle | Jing-Jing HU Jin-Song LIU Use of neuromodulators in the treatment of irritable bowel syndrome Yixue xinzhi zazhi irritable bowel syndrome neuromodulator mental and psychological abnormality treatment |
| title | Use of neuromodulators in the treatment of irritable bowel syndrome |
| title_full | Use of neuromodulators in the treatment of irritable bowel syndrome |
| title_fullStr | Use of neuromodulators in the treatment of irritable bowel syndrome |
| title_full_unstemmed | Use of neuromodulators in the treatment of irritable bowel syndrome |
| title_short | Use of neuromodulators in the treatment of irritable bowel syndrome |
| title_sort | use of neuromodulators in the treatment of irritable bowel syndrome |
| topic | irritable bowel syndrome neuromodulator mental and psychological abnormality treatment |
| url | https://yxxz.whuznhmedj.com/storage/attach/2112/epcbCIktARMbxEwYcb212jnulKbkfvKw8Fr3fpU0.pdf |
| work_keys_str_mv | AT jingjinghu useofneuromodulatorsinthetreatmentofirritablebowelsyndrome AT jinsongliu useofneuromodulatorsinthetreatmentofirritablebowelsyndrome |