Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial Agents

This research explores the green route synthesis in producing silver nanoparticles (Ag NPs) mediated by Cassia alata leaf and Zingiber officinale extracts using the maceration method as bioreductor agents. Furthermore, this study also investigates the potential antibacterial application of the Ag NP...

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Main Authors: Mecca Abdia Mtutia Hasan, Akbar Evander Maulana, Ningsih Amilia Puspita, Syabila Oktavia Nur, Laily Tsaniyatur Rizqi Nurul, Nikmah Ainun, Subradra ST. Ulfawanti Intan, Taufiq Ahmad
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2025/34/bioconf_icolist2024_01004.pdf
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author Mecca Abdia Mtutia Hasan
Akbar Evander Maulana
Ningsih Amilia Puspita
Syabila Oktavia Nur
Laily Tsaniyatur Rizqi Nurul
Nikmah Ainun
Subradra ST. Ulfawanti Intan
Taufiq Ahmad
author_facet Mecca Abdia Mtutia Hasan
Akbar Evander Maulana
Ningsih Amilia Puspita
Syabila Oktavia Nur
Laily Tsaniyatur Rizqi Nurul
Nikmah Ainun
Subradra ST. Ulfawanti Intan
Taufiq Ahmad
author_sort Mecca Abdia Mtutia Hasan
collection DOAJ
description This research explores the green route synthesis in producing silver nanoparticles (Ag NPs) mediated by Cassia alata leaf and Zingiber officinale extracts using the maceration method as bioreductor agents. Furthermore, this study also investigates the potential antibacterial application of the Ag NPs against bacteria Staphylococcus aureus. The particle size of Ag NPs derived from Cassia alata leaf extract was around 42.5 ± 0.3 nm, smaller than those from Zingiber officinale extract with a value of 44.4 ± 0.6 nm. In addition, Fourier-transform infrared spectroscopy data analysis revealed that the OH, C=O, and CH phenolic groups were involved in reducing Ag+ to Ag0. Meanwhile, the results of antibacterial activity showed that Ag NPs synthesized using Cassia alata leaf extract offered more excellent antibacterial activity than those from the Zingiber officinale extract. The inhibition zone diameter of the Ag NPs synthesized using Cassia alata leaf extract was 14.5 ± 2.2 mm. In comparison, the Ag NPs synthesized from the Zingiber officinale extract had an inhibition zone diameter of 10.5 ± 0.9 mm. Therefore, the results of this work support the development of environmentally friendly nanotechnology-based antibacterial therapy.
format Article
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institution Kabale University
issn 2117-4458
language English
publishDate 2025-01-01
publisher EDP Sciences
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series BIO Web of Conferences
spelling doaj-art-9538d094beaf4f7ca798020465821a952025-08-20T03:51:08ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011830100410.1051/bioconf/202518301004bioconf_icolist2024_01004Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial AgentsMecca Abdia Mtutia Hasan0Akbar Evander Maulana1Ningsih Amilia Puspita2Syabila Oktavia Nur3Laily Tsaniyatur Rizqi Nurul4Nikmah Ainun5Subradra ST. Ulfawanti Intan6Taufiq Ahmad7SMA Unggulan HAF-SA BPPT Genggong, Pesantren Zainul Hasan GenggongSMA Unggulan HAF-SA BPPT Genggong, Pesantren Zainul Hasan GenggongSMA Unggulan HAF-SA BPPT Genggong, Pesantren Zainul Hasan GenggongSMA Unggulan HAF-SA BPPT Genggong, Pesantren Zainul Hasan GenggongSMA Unggulan HAF-SA BPPT Genggong, Pesantren Zainul Hasan GenggongDepartment of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri MalangDepartment of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri MalangDepartment of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri MalangThis research explores the green route synthesis in producing silver nanoparticles (Ag NPs) mediated by Cassia alata leaf and Zingiber officinale extracts using the maceration method as bioreductor agents. Furthermore, this study also investigates the potential antibacterial application of the Ag NPs against bacteria Staphylococcus aureus. The particle size of Ag NPs derived from Cassia alata leaf extract was around 42.5 ± 0.3 nm, smaller than those from Zingiber officinale extract with a value of 44.4 ± 0.6 nm. In addition, Fourier-transform infrared spectroscopy data analysis revealed that the OH, C=O, and CH phenolic groups were involved in reducing Ag+ to Ag0. Meanwhile, the results of antibacterial activity showed that Ag NPs synthesized using Cassia alata leaf extract offered more excellent antibacterial activity than those from the Zingiber officinale extract. The inhibition zone diameter of the Ag NPs synthesized using Cassia alata leaf extract was 14.5 ± 2.2 mm. In comparison, the Ag NPs synthesized from the Zingiber officinale extract had an inhibition zone diameter of 10.5 ± 0.9 mm. Therefore, the results of this work support the development of environmentally friendly nanotechnology-based antibacterial therapy.https://www.bio-conferences.org/articles/bioconf/pdf/2025/34/bioconf_icolist2024_01004.pdf
spellingShingle Mecca Abdia Mtutia Hasan
Akbar Evander Maulana
Ningsih Amilia Puspita
Syabila Oktavia Nur
Laily Tsaniyatur Rizqi Nurul
Nikmah Ainun
Subradra ST. Ulfawanti Intan
Taufiq Ahmad
Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial Agents
BIO Web of Conferences
title Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial Agents
title_full Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial Agents
title_fullStr Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial Agents
title_full_unstemmed Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial Agents
title_short Green Route Synthesis of Silver Nanoparticles Mediated by Cassia alata Leaf and Zingiber officinale Extracts as Excellent Antibacterial Agents
title_sort green route synthesis of silver nanoparticles mediated by cassia alata leaf and zingiber officinale extracts as excellent antibacterial agents
url https://www.bio-conferences.org/articles/bioconf/pdf/2025/34/bioconf_icolist2024_01004.pdf
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